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scopus(14)
A pharmacokinetic model of oral methylphenidate in the rat and effects on behavior
ArticleAbstract: Most animal studies using methylphenidate (MP) do not administer it the same way it is administeredPalabras claves:Attention Deficit Hyperactivity Disorder, Dopamine transporter, methylphenidate, Psychostimulant, ritalinAutores:Cooper T., David Edward Komatsu, Hadjiargyrou M., Hwang Y., Robison L.S., Steier J., Swanson J.M., Thanos P.K., Volkow N.D.Fuentes:scopusChronic exposure to methylphenidate impairs appendicular bone quality in young rats
ArticleAbstract: Methylphenidate (MP) is a psychostimulant widely prescribed to treat Attention Deficit HyperactivityPalabras claves:Biomechanics, DXA, Growth suppression, methylphenidate, TestosteroneAutores:Ananth M., David Edward Komatsu, Hadjiargyrou M., Janda H.A., John C.M., Mary M.N., Robison L.S., Swanson J.M., Thanos P.K., Volkow N.D.Fuentes:scopusChronic oral methylphenidate treatment increases microglial activation in rats
ArticleAbstract: Methylphenidate (MP) is a widely prescribed psychostimulant used to treat attention deficit hyperactPalabras claves:Attention Deficit Hyperactivity Disorder, Autoradiography, inflammation, methylphenidate, Microglia, ritalinAutores:Carias E., David Edward Komatsu, Delis F., Eiden R., Hadjiargyrou M., Hamilton J., Quattrin T., Robison L.S., Thanos P.K.Fuentes:scopusBrief and extended abstinence from chronic oral methylphenidate treatment produces reversible behavioral and physiological effects
ArticleAbstract: Methylphenidate (MP) is a commonly prescribed psychostimulant to individuals with Attention DeficitPalabras claves:anxiety, Attention Deficit Hyperactivity Disorder, methylphenidate, Psychostimulant, ritalinAutores:Carias E., Connor C., David Edward Komatsu, Hadjiargyrou M., Kalinowski L., Mackintosh M., Martin C., Popoola D., Richer K., Smith L., Somanesan R., Thanos P.K.Fuentes:scopusActivation of the transcription factor HIF-1 and its target genes, VEGF, HO-1, iNOS, during fracture repair
ArticleAbstract: One of the immediate sequelae of bone fracture is regional hypoxia resulting from vasculature disrupPalabras claves:Angiogenesis, bone, Callus, Fracture, HIF-1α, HypoxiaAutores:David Edward Komatsu, Hadjiargyrou M.Fuentes:scopusEnhanced bone regeneration associated with decreased apoptosis in mice with partial HIF-1α deficiency
ArticleAbstract: HIF-1α activates genes under hypoxia and was hypothesized to regulate bone regeneration. SurprisinglPalabras claves:apoptosis, bone, Fracture, Hypoxia-inducible factor 1α, REGENERATIONAutores:Bosch-Marce M., David Edward Komatsu, Hadjiargyrou M., Semenza G.L.Fuentes:scopusIdentification and Characterization of a Synthetic Osteogenic Peptide
ArticleAbstract: Osteoporosis is the most common metabolic bone disorder and its management represents a tremendous pPalabras claves:bioinformatics, Calcitonin, microCT, OSTEOPOROSIS, OvariectomyAutores:David Edward Komatsu, Hadjiargyrou M., Pentyala S.N., Trasolini N.A., Udin S.M.Z.Fuentes:scopusIdentification of the microRNA transcriptome during the early phases of mammalian fracture repair
ArticleAbstract: Fracture repair is a complex process that involves multiple biological processes requiring spatiotemPalabras claves:bone, MiRNA, REGENERATION, regulation, Transcriptional, TranscriptomeAutores:David Edward Komatsu, Hadjiargyrou M., Zhi J.Fuentes:scopusThe Therapeutic Potential of MicroRNAs as Orthobiologics for Skeletal Fractures
ReviewAbstract: The repair of a fractured bone is critical to the well-being of humans. Failure of the repair procesPalabras claves:BONE DEFECT, exosome, Fracture repair, MICRORNA (miRNA), nonunion, ORTHOBIOLOGIC, OSTEOPOROSISAutores:David Edward Komatsu, Hadjiargyrou M.Fuentes:scopusWeekday-only chronic oral methylphenidate self-administration in male rats: Reversibility of the behavioral and physiological effects
ArticleAbstract: Methylphenidate (MP) is a commonly prescribed psychostimulant for Attention Deficit Hyperactivity DiPalabras claves:anxiety, Attention Deficit Hyperactivity Disorder, Depression, methylphenidate, Psychostimulant, ritalin, SOCIAL BEHAVIORAutores:Carias E., David Edward Komatsu, Fricke D., Hadjiargyrou M., Kalinowski L., Martin C., Popoola D., Smith L., Somanesan R., Thanos P.K., Vijayashanthar A.Fuentes:scopus