Determination of debrisoquine and 4-hydroxydebrisoquine by high-performance liquid chromatography: Application to the evaluation of CYP2D6 genotype and debrisoquine metabolic ratio relationship

Article

Abstract: The drug-metabolizing cytochrome P450 (CYP) enzyme CYP2D6 is involved in the metabolism of several c

Palabras claves:

CYP2D6, debrisoquine, HPLC, Metabolic ratio

Autores:

Adrián LLerena, Berecz R., Cáceres M.C., Cobaleda J., Dorado P., González I.

Fuentes:

scopus