Mostrando 10 resultados de: 16
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Journal of Clinical Endocrinology and Metabolism(3)
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Journal of Steroid Biochemistry and Molecular Biology(2)
Annals of the American Thoracic Society(1)
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scopus(16)
Analysis of novel heterozygous mutations in the CYP11B2 gene causing congenital aldosterone synthase deficiency and literature review
ArticleAbstract: Aldosterone synthase deficiency (ASD) is a rare autosomal recessive disorder characterized by severePalabras claves:Aldosterone synthesis, CYP11B2 mutations, Hypoaldosteronism, next-generation sequencingAutores:Chen S., Gong F., Jiang J., Liu J., Lu L., Lu Z., Miao H., Pan H., Richard J. Auchus, Yu Z., Zhu H.Fuentes:scopusConversion of abiraterone to D4A drives anti-tumour activity in prostate cancer
ArticleAbstract: Prostate cancer resistance to castration occurs because tumours acquire the metabolic capability ofPalabras claves:Autores:Alyamani M., Bishop A., Bunch D., Dreicer R., Garcia J., Li Z., Liu J., Richard J. Auchus, Sharifi N., Upadhyay S.K.Fuentes:scopusCatalytically relevant electrostatic interactions of cytochrome P450c17 (CYP17A1) and cytochrome b<inf>5</inf>
ArticleAbstract: Background: Cytochrome b5 (b5) stimulates the 17,20-lyase activity of cytochrome P450c17 (CYP17A1).Palabras claves:Autores:Anderson S.M., Forsberg S.E., Liu J., Peng H.M., Richard J. Auchus, Tran H.T.Fuentes:scopusAbiraterone inhibits 3β-hydroxysteroid dehydrogenase: A rationale for increasing drug exposure in castration-resistant prostate cancer
ArticleAbstract: Purpose: Treatment with abiraterone (abi) acetate prolongs survival in castration-resistant prostatePalabras claves:Autores:Chang K.H., Evaul K., Li R., Liu J., Richard J. Auchus, Sharifi N., Sharma K.K., Yoshimoto J.A.Fuentes:scopusFunctional characterization of the G162R and D216H genetic variants of human CYP17A1
ArticleAbstract: Cytochrome P450 17A1 (CYP17A1) is a dual-function enzyme catalyzing reactions necessary for cortisolPalabras claves:CYP17A1, Cytochrome p450, Proteasome, steroidogenesis, UbiquitinationAutores:Capper C.P., Hollenberg P.F., Johnson M.D., Larios J.M., Liu J., McIntosh L.R., Osawa Y., Rae J.M., Richard J. AuchusFuentes:scopusGerm cell neoplasia in situ complicating 17β-hydroxysteroid dehydrogenase type 3 deficiency
ReviewAbstract: 17β-hydroxysteroid dehydrogenase type 3 (17βHSD3)deficiency is an autosomal recessive disorder of maPalabras claves:17β-hydroxysteroid dehydrogenase type 3 deficiency, 46XY disorder of sex development, Mutations, Puberty, Testosterone, VirilizationAutores:Eugster E.A., Folsom L.J., Hjaige M., Liu J., Richard J. AuchusFuentes:scopusExpression in escherichia coli, purification, and functional reconstitution of human steroid 5α-reductases
ArticleAbstract: The potent androgen 5α-dihydrotestosterone irreversibly derives from testosterone via the activity oPalabras claves:5α-reductase, androgen, Dihydrotestosterone, prostate, steroidogenesisAutores:Han B., Im S.C., Liu J., Peng H.M., Qiao J., Richard J. Auchus, Valentín-Goyco J.Fuentes:scopusExhaled nitric oxide decreases during academic examination stress in asthma
ArticleAbstract: Rationale: Fractional exhaled nitric oxide (FENO) is known to vary with multiple endogenous and exogPalabras claves:Asthma, Depression, Exhaled nitric oxide, Psychological stress, Salivary cortisolAutores:Ana Francisca Trueba, Liu J., Richard J. Auchus, Ritz T., Rosenfield D.Fuentes:scopusEctopic prolactin secretion from a perivascular epithelioid cell tumor (PEComa)
Conference ObjectAbstract: Background: The diagnosis of ectopic pituitary hormone secretion requires abnormally high circulatinPalabras claves:Autores:Barkan A., Camelo-Piragua S., Korytnaya E., Liu J., Richard J. Auchus, Sullivan S.Fuentes:scopusOpposing effects of cyclooxygenase-2 (COX-2) on estrogen receptor β (ERβ) response to 5α-reductase inhibition in prostate epithelial cells
ArticleAbstract: Current pharmacotherapies for symptomatic benign prostatic hyperplasia (BPH), an androgen receptor-dPalabras claves:Autores:DeFranco D.B., Frahm K.A., Grubisha M.J., Liu J., Liu T.T., Richard J. Auchus, Ricke W.A., Wendell S.G.Fuentes:scopus