Mostrando 10 resultados de: 16
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Journal of Clinical Endocrinology and Metabolism(3)
Journal of Biological Chemistry(2)
Journal of Steroid Biochemistry and Molecular Biology(2)
Annals of the American Thoracic Society(1)
Cell(1)
Analysis of novel heterozygous mutations in the CYP11B2 gene causing congenital aldosterone synthase deficiency and literature review
ArticleAbstract: Aldosterone synthase deficiency (ASD) is a rare autosomal recessive disorder characterized by severePalabras claves:Aldosterone synthesis, CYP11B2 mutations, Hypoaldosteronism, next-generation sequencingAutores:Chen S., Gong F., Jiang J., Liu J., Lu L., Lu Z., Miao H., Pan H., Richard J. Auchus, Yu Z., Zhu H.Fuentes:scopusConversion of abiraterone to D4A drives anti-tumour activity in prostate cancer
ArticleAbstract: Prostate cancer resistance to castration occurs because tumours acquire the metabolic capability ofPalabras claves:Autores:Alyamani M., Bishop A., Bunch D., Dreicer R., Garcia J., Li Z., Liu J., Richard J. Auchus, Sharifi N., Upadhyay S.K.Fuentes:scopusCatalytically relevant electrostatic interactions of cytochrome P450c17 (CYP17A1) and cytochrome b<inf>5</inf>
ArticleAbstract: Background: Cytochrome b5 (b5) stimulates the 17,20-lyase activity of cytochrome P450c17 (CYP17A1).Palabras claves:Autores:Anderson S.M., Forsberg S.E., Liu J., Peng H.M., Richard J. Auchus, Tran H.T.Fuentes:scopusAbiraterone inhibits 3β-hydroxysteroid dehydrogenase: A rationale for increasing drug exposure in castration-resistant prostate cancer
ArticleAbstract: Purpose: Treatment with abiraterone (abi) acetate prolongs survival in castration-resistant prostatePalabras claves:Autores:Chang K.H., Evaul K., Li R., Liu J., Richard J. Auchus, Sharifi N., Sharma K.K., Yoshimoto J.A.Fuentes:scopusFunctional characterization of the G162R and D216H genetic variants of human CYP17A1
ArticleAbstract: Cytochrome P450 17A1 (CYP17A1) is a dual-function enzyme catalyzing reactions necessary for cortisolPalabras claves:CYP17A1, Cytochrome p450, Proteasome, steroidogenesis, UbiquitinationAutores:Capper C.P., Hollenberg P.F., Johnson M.D., Larios J.M., Liu J., McIntosh L.R., Osawa Y., Rae J.M., Richard J. AuchusFuentes:scopusGerm cell neoplasia in situ complicating 17β-hydroxysteroid dehydrogenase type 3 deficiency
ReviewAbstract: 17β-hydroxysteroid dehydrogenase type 3 (17βHSD3)deficiency is an autosomal recessive disorder of maPalabras claves:17β-hydroxysteroid dehydrogenase type 3 deficiency, 46XY disorder of sex development, Mutations, Puberty, Testosterone, VirilizationAutores:Eugster E.A., Folsom L.J., Hjaige M., Liu J., Richard J. AuchusFuentes:scopusExpression in escherichia coli, purification, and functional reconstitution of human steroid 5α-reductases
ArticleAbstract: The potent androgen 5α-dihydrotestosterone irreversibly derives from testosterone via the activity oPalabras claves:5α-reductase, androgen, Dihydrotestosterone, prostate, steroidogenesisAutores:Han B., Im S.C., Liu J., Peng H.M., Qiao J., Richard J. Auchus, Valentín-Goyco J.Fuentes:scopusExhaled nitric oxide decreases during academic examination stress in asthma
ArticleAbstract: Rationale: Fractional exhaled nitric oxide (FENO) is known to vary with multiple endogenous and exogPalabras claves:Asthma, Depression, Exhaled nitric oxide, Psychological stress, Salivary cortisolAutores:Ana Francisca Trueba, Liu J., Richard J. Auchus, Ritz T., Rosenfield D.Fuentes:scopusEctopic prolactin secretion from a perivascular epithelioid cell tumor (PEComa)
Conference ObjectAbstract: Background: The diagnosis of ectopic pituitary hormone secretion requires abnormally high circulatinPalabras claves:Autores:Barkan A., Camelo-Piragua S., Korytnaya E., Liu J., Richard J. Auchus, Sullivan S.Fuentes:scopusOpposing effects of cyclooxygenase-2 (COX-2) on estrogen receptor β (ERβ) response to 5α-reductase inhibition in prostate epithelial cells
ArticleAbstract: Current pharmacotherapies for symptomatic benign prostatic hyperplasia (BPH), an androgen receptor-dPalabras claves:Autores:DeFranco D.B., Frahm K.A., Grubisha M.J., Liu J., Liu T.T., Richard J. Auchus, Ricke W.A., Wendell S.G.Fuentes:scopus