Mostrando 10 resultados de: 22
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Journal of Alzheimer's Disease(3)
Biochimica et Biophysica Acta - Molecular Basis of Disease(2)
Mechanisms of Ageing and Development(2)
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Advances in Alzheimer's Disease(1)
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scopus(22)
Dietary resveratrol prevents Alzheimer's markers and increases life span in SAMP8
ArticleAbstract: Resveratrol is a polyphenol that is mainly found in grapes and red wine and has been reported to bePalabras claves:Alzheimer's disease, AMPK, Memory impairment, Resveratrol, Senescence, Sirtuin 1, Tau, β-AmyloidAutores:Antoni Camins, Bayod S., Canudas A.M., Casadesús G., Del Valle J., Pallás M., Pelegrí Gabalda C., Porquet D., Sanfeliu C., Vicente A., Vilaplana J.Fuentes:scopusActivation of Akt by lithium: Pro-survival pathways in aging
ArticleAbstract: The effects of lithium on senescence were investigated using the senescence-accelerated mouse pronePalabras claves:aging, Lithium chloride, Neurodegeneration, neuroprotection, SAMP8Autores:Antoni Camins, Casadesús G., Chou S.P., Pallás M., Smith M.A., Tajes M., Yeste-Velasco M., Zhu X.Fuentes:scopusExperimental models for aging and their potential for novel drug discovery
ReviewAbstract: Background: An interesting area of scientific research is the development of potential antiaging druPalabras claves:aging, Heterogeneous mice model, IGF-1, mTOR, Resveratrol, SAMP8, SirtuinsAutores:Antoni Camins, Auladell C., Busquets O., Casadesús G., Ettcheto M., Folch J., Miguel Marin, Olloquequi J., Pallás M., Sanchez-Lopez E., Zárate C.B.Fuentes:scopusEarly Preclinical Changes in Hippocampal CREB-Binding Protein Expression in a Mouse Model of Familial Alzheimer’s Disease
ArticleAbstract: The molecular basis of memory loss in Alzheimer’s disease (AD), the main cause of senile dementia, iPalabras claves:Alzheimer disease, APPswe/PS1dE9, CBP, CREB, hippocampusAutores:Abad S., Antoni Camins, Auladell C., Busquets O., Carro E., Casadesús G., Ettcheto M., Folch J., Olloquequi J., Pallás M., Pedros I., Petrov D., Sanchez-Lopez E., Zárate C.B.Fuentes:scopusEarly alterations in energy metabolism in the hippocampus of APPswe/PS1dE9 mouse model of Alzheimer's disease
ArticleAbstract: The present study had focused on the behavioral phenotype and gene expression profile of molecules rPalabras claves:Alzheimer's disease, APPswe/PS1dE9, hippocampus, insulin receptor, Mitochondria, TauAutores:Allgaier M., Antoni Camins, Auladell C., Barroso E., Casadesús G., Folch J., Pallás M., Pedros I., Petrov D., Sureda F.X., Vázquez-Carrera M., Zárate C.B.Fuentes:scopusNeuronal cell cycle re-entry markers are altered in the senescence accelerated mouse P8 (SAMP8)
ArticleAbstract: Senescence-accelerated mice 8 (SAMP8), a model of aging, display many established pathological featuPalabras claves:aging, Alzheimer's disease, CDK5, cell cycle, GSK3β, TauAutores:Antoni Camins, Casadesús G., Gutiérrez-Cuesta J., Jiménez A., Lee H.g., Ortuo-Sahagún D., Pallás M., Smith M.A., Tajes M.Fuentes:scopusNeuroprotection by c-Jun NH<inf>2</inf>-terminal kinase inhibitor SP600125 against potassium deprivation-induced apoptosis involves the Akt pathway and inhibition of cell cycle reentry
ArticleAbstract: Increasing evidence implicates the c-Jun NH2-terminal kinase (JNK) pathway in the regulation of apopPalabras claves:Akt, c-Jun NH2-terminal kinase, cell cycle, Cerebellar granule cells, SP600125Autores:Antoni Camins, Casadesús G., Folch J., Pallás M., Smith M.A., Yeste-Velasco M.Fuentes:scopusNeuroprotective effects of caffeine against complex I inhibition-induced apoptosis are mediated by inhibition of the ATM/p53/E2F-1 path in cerebellar granule neurons
ArticleAbstract: The aim of the present study was to evaluate the neuroprotective effects of caffeine, an inhibitor oPalabras claves:Ataxia telangiectasia mutated, caffeine, Cerebellar granule cells, Complex I inhibition, E2F-1, MPP +Autores:Alvira D., Antoni Camins, Casadesús G., Folch J., Pallás M., Smith M.A., Yeste-Velasco M.Fuentes:scopusNeuroprotective effects of the amylin analog, pramlintide, on Alzheimer's disease are associated with oxidative stress regulation mechanisms
ArticleAbstract: Administration of the recombinant analog of the pancreatic amyloid amylin, Pramlintide, has shown thPalabras claves:Alzheimer's disease, amylin, metabolism, neuroprotection, Oxidative Stress, pramlintideAutores:Antoni Camins, Blair J., Casadesús G., Corrigan R., Grizzanti J., Lee H.g., Mey M., Pallás M., Patrick S.Fuentes:scopusHigh-fat diet-induced deregulation of hippocampal insulin signaling and mitochondrial homeostasis deficiences contribute to Alzheimer disease pathology in rodents
ArticleAbstract: Global obesity is a pandemic status, estimated to affect over 2 billion people, that has resulted inPalabras claves:Alzheimer disease, APPswe/PS1dE9, hippocampus, insulin receptor, Mitochondria, TauAutores:Antoni Camins, Artiach G., Barroso E., Carro E., Casadesús G., Ferrer I., Folch J., Pallás M., Pedros I., Petrov D., Sureda F.X., Vázquez-Carrera M., Zárate C.B.Fuentes:scopus