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Neuronal cell cycle re-entry markers are altered in the senescence accelerated mouse P8 (SAMP8)
ArticleAbstract: Senescence-accelerated mice 8 (SAMP8), a model of aging, display many established pathological featuPalabras claves:aging, Alzheimer's disease, CDK5, cell cycle, GSK3β, TauAutores:Antoni Camins, Casadesús G., Gutiérrez-Cuesta J., Jiménez A., Lee H.g., Ortuo-Sahagún D., Pallás M., Smith M.A., Tajes M.Fuentes:scopusNeuroprotective effects of SB-415286 on hydrogen peroxide-induced cell death in B65 rat neuroblastoma cells and neurons
ArticleAbstract: Glycogen synthase kinase-3 (GSK-3) is involved in the pathogenesis of several neurodegenerative disePalabras claves:B65 Neuroblastoma cells, Cerebellar granule cells, H O 2 2, Lithium, Oxidative Stress, SB-415286Autores:Antoni Camins, Casadesús G., Folch J., Pallás M., Pizarro J.G., Rimbau V., Smith M.A., Yeste-Velasco M.Fuentes:scopusNeuroprotective effects of caffeine against complex I inhibition-induced apoptosis are mediated by inhibition of the ATM/p53/E2F-1 path in cerebellar granule neurons
ArticleAbstract: The aim of the present study was to evaluate the neuroprotective effects of caffeine, an inhibitor oPalabras claves:Ataxia telangiectasia mutated, caffeine, Cerebellar granule cells, Complex I inhibition, E2F-1, MPP +Autores:Alvira D., Antoni Camins, Casadesús G., Folch J., Pallás M., Smith M.A., Yeste-Velasco M.Fuentes:scopusIncreased permeability of blood-brain barrier on the hippocampus of a murine model of senescence
ArticleAbstract: SAMP8 mice show several indicative characteristics of accelerated aging and have been used to studyPalabras claves:blood-brain barrier, Confocal microscopy, hippocampus, IgG quantification, Immunohistochemistry, mouse, SAMP8, SenescenceAutores:Antoni Camins, Canudas A.M., Casadesús G., Del Valle J., Pallás M., Pelegrí Gabalda C., Smith M.A., Vilaplana J.Fuentes:scopusc-Jun N-terminal Kinase 1 ablation protects against metabolic-induced hippocampal cognitive impairments
ArticleAbstract: Abstract: The development of metabolic alterations like insulin resistance has been associated withPalabras claves:c-Jun N-terminal Kinase 1, Cognitive impairments, high-fat dietAutores:Antoni Camins, Auladell C., Bulló M., Busquets O., Casadesús G., Castro-Torres R.D., Eritja À., Espinosa-Jimenez T., Ettcheto M., Folch J., Olloquequi J., Verdaguer E., Zárate C.B.Fuentes:scopusThe effect of mGluR2 activation on signal transduction pathways and neuronal cell survival
ArticleAbstract: In earlier studies, we found profound alterations in specific signal transduction pathways such as mPalabras claves:ERK, mGluR2, neuroprotectionAutores:Antoni Camins, Casadesús G., Lee H.g., Nakanishi S., O'Neill M.J., Pallás M., Perry G., Smith M.A., Zhu X.Fuentes:scopus