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Diabetes Technology and Therapeutics(2)
Growth Hormone and IGF Research(2)
Journal of Clinical Endocrinology and Metabolism(2)
European Journal of Endocrinology(1)
Science Translational Medicine(1)
Comparison of oral insulin spray and subcutaneous regular insulin at mealtime in type 1 diabetes
ArticleAbstract: Background: The aim of this study was to compare the glucose pharmacodynamics after oral spray insulPalabras claves:Autores:Bernstein G., Jaime Guevara-Aguirre, Marco Guevara-Aguirre, Rosenbloom A.L., Saavedra J.Fuentes:scopusAssessing insulin sensitivity and resistance in syndromes of severe short stature
ArticleAbstract: Individuals affected with two genetic syndromes identified in Ecuador have severe short stature andPalabras claves:Homeostatic minimal models, Insulin Resistance, Metabolic phenotypeAutores:Antonio Wenceslao Danilo Gavilanes, Carolina Guevara, Daniela Lescano, Enrique Terán, Guevara A., Jaime Guevara-Aguirre, Procel P., Saavedra J., Wasserfall C.H.Fuentes:scopusBeneficial Effects of Addition of Oral Spray Insulin (Oralin) on Insulin Secretion and Metabolic Control in Subjects with Type 2 Diabetes Mellitus Suboptimally Controlled on Oral Hypoglycemic Agents
ArticleAbstract: The aim of this study was to determine the metabolic effect and the safety of a novel oral insulin sPalabras claves:Autores:Guevara M., Jaime Guevara-Aguirre, Mihic M., Modi P., Saavedra J.Fuentes:scopusGH receptor deficiency in ecuadorian adults is associated with obesity and enhanced insulin sensitivity
Conference ObjectAbstract: Context: Ecuadorian subjects with GH receptor deficiency (GHRD) have not developed diabetes, despitePalabras claves:Autores:Alfaras I., Balasubramanian P., Carolina Guevara, De Cabo R., Di Biase S., Enrique Terán, Jaime Guevara-Aguirre, Longo V.D., Marco Guevara-Aguirre, Narvaez L., Procel P., Rosenbloom A.L., Saavedra J.Fuentes:googlescopusEffects of heterozygosity for the E180 splice mutation causing growth hormone receptor deficiency in Ecuador on IGF-I, IGFBP-3, and stature
ArticleAbstract: Context & objective: The Ecuadorian GH receptor deficiency (GHRD)/Laron syndrome population is the oPalabras claves:GH receptor deficiency, growth, IGF-I, IGFBP-3, Laron syndromeAutores:Baumbach L., Jaime Guevara-Aguirre, Marco Guevara-Aguirre, Rosenbloom A.L., Saavedra J., Shuster J., Yariz K.Fuentes:scopusGrowth hormone receptor deficiency is associated with a major reduction in pro-aging signaling, cancer, and diabetes in humans
ArticleAbstract: Mutations in growth signaling pathways extend life span, as well as protect against age-dependent DNPalabras claves:Autores:Balasubramanian P., Cheng C.W., Cohen P., De Cabo R., Hwang D., Ingles S., Jaime Guevara-Aguirre, Longo V.D., Madia F., Marco Guevara-Aguirre, Martin-Montalvo A., Saavedra J., Wei M.Fuentes:scopusIntrauterine and postnatal growth failure with normal GH/IGF1 axis and insulin-resistant diabetes in a consanguineous kinship
ArticleAbstract: Objective: To describe the clinical and biochemical features, and perform molecular analysis for canPalabras claves:Autores:Fang P., Hwa V., Jaime Guevara-Aguirre, Kerns S.L., Marco Guevara-Aguirre, Ostrer H., Procel P., Rosenbloom A.L., Rosenfeld R.G., Saavedra J.Fuentes:scopusRecommended IGF-I dosage causes greater fat accumulation and osseous maturation than lower dosage and may compromise long-term growth effects
ArticleAbstract: Context: The maximum dose of IGF-I recommended for treatment of GH insensitivity is commonly used. OPalabras claves:Autores:Jaime Guevara-Aguirre, Marco Guevara-Aguirre, Procel P., Rosenbloom A.L., Saavedra J.Fuentes:scopus