Mostrando 10 resultados de: 46
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scopus(46)
3,4-Methylenedioxymethamphetamine enhances kainic acid convulsive susceptibility
ArticleAbstract: Kainic acid (KA) causes seizures and neuronal loss in the hippocampus. The present study investigatePalabras claves:Calbindin, Calretinin, Kainic acid, MDMA, Parvalbumin, seizuresAutores:Abad S., Antoni Camins, Auladell C., Camarasa J., Escubedo E., Junyent F., Pallás M., Pubill D.Fuentes:scopusA chronological review of potential disease-modifying therapeutic strategies for Alzheimer's disease
ReviewAbstract: Late-onset Alzheimer’s disease (LOAD) is a neurodegenerative disorder that has become a worldwide hePalabras claves:Alzheimer’s disease, calcium, ER stress, glutamate, Neurodegeneration, neuroinflammation, Oxidative Stress, Parkinson’s DiseaseAutores:Antoni Camins, Auladell C., Busquets O., Espinosa-Jimenez T., Ettcheto M., Verdaguer E.Fuentes:scopusBenzodiazepines and Related Drugs as a Risk Factor in Alzheimer's Disease Dementia
ArticleAbstract: Benzodiazepines (BZDs) and Z-drugs are compounds widely prescribed in medical practice due to theirPalabras claves:Alzheimer's disease, benzodiazepines, COGNITION, dementia, RISK FACTORSAutores:Antoni Camins, Auladell C., Bulló M., Busquets O., Cano A., Castro-Torres R.D., Ettcheto M., Folch J., García M.L., Manzine P.R., Olloquequi J., Sanchez-Lopez E., Zárate C.B.Fuentes:scopusC-Jun N-Terminal Kinases in Alzheimer's Disease: A Possible Target for the Modulation of the Earliest Alterations
ReviewAbstract: Given the highly multifactorial origin of Alzheimer's disease (AD) neuropathology, disentangling andPalabras claves:Alzheimer's disease, Amyloid-β, axonal transport, hyperphosphorylated tau, JNK, synapse lossAutores:Antoni Camins, Auladell C., Busquets O., Castro-Torres R.D., Ettcheto M., Parcerisas A., Verdaguer E., Zárate C.B.Fuentes:scopusAnti-inflammatory role of Leptin in glial cells through p38 MAPK pathway inhibition
ArticleAbstract: Background In the present work, we studied the modulatory effect of Leptin (Lep) against pro-inflammPalabras claves:Caspase-3, Cytochrome-c, Glial cells, iNOS, leptin, p38 MAPKAutores:Antoni Camins, Auladell C., Busquets O., Ettcheto M., Folch J., Martí A., Martínez N., Miguel Marin, Patraca I., Pedros I., Sureda F.X., Zárate C.B.Fuentes:scopusAntiapoptotic drugs: A therapautic strategy for the prevention of neurodegenerative diseases
ReviewAbstract: The purpose of this review is to discuss potential pathways involved in the pathogenesis of neurodegPalabras claves:Alzheimer's disease, apoptosis, Cyclin-dependent kinases, Glutamate receptors, Neuronal cell death, Neuroprotective drugs. apoptosis, Parkinson's DiseaseAutores:Antoni Camins, Auladell C., Canudas A.M., Folch J., Junyent F., Pallás M., Pelegrí Gabalda C., Sureda F.X., Verdaguer E., Vilaplana J., Zárate C.B.Fuentes:scopusAntiapoptotic effects of roscovitine on camptothecin-induced DNA damage in neuroblastoma cells
ArticleAbstract: In the present study dopaminergic neuroblastoma B65 cells were exposed to Camptothecin (CPT) (0.5-10Palabras claves:Ataxia telangiectasia mutated, camptothecin, cell cycle, RoscovitineAutores:Antoni Camins, Auladell C., Folch J., Junyent F., Pallás M., Pizarro J.G., Verdaguer E., Zárate C.B.Fuentes:scopusAging biology: A new frontier for drug discovery
ReviewAbstract: Introduction: The prevalence of age-related pathologies, such as cardiovascular disease, neurodegenePalabras claves:Autores:Antoni Camins, Auladell C., Folch J., Junyent F., Pallás M., Verdaguer E., Zárate C.B.Fuentes:scopusEarly Preclinical Changes in Hippocampal CREB-Binding Protein Expression in a Mouse Model of Familial Alzheimer’s Disease
ArticleAbstract: The molecular basis of memory loss in Alzheimer’s disease (AD), the main cause of senile dementia, iPalabras claves:Alzheimer disease, APPswe/PS1dE9, CBP, CREB, hippocampusAutores:Abad S., Antoni Camins, Auladell C., Busquets O., Carro E., Casadesús G., Ettcheto M., Folch J., Olloquequi J., Pallás M., Pedros I., Petrov D., Sanchez-Lopez E., Zárate C.B.Fuentes:scopusDual mkk4 and mkk7 gene deletion in adult mouse causes an impairment of hippocampal immature granule cells
ArticleAbstract: (1) Background: The c-Jun-NH2-terminal protein kinase (JNK) is a mitogen-activated protein kinase inPalabras claves:Cre-LoxP, DCX, hippocampus, MKK4, MKK7, PJNKAutores:Antoni Camins, Auladell C., Caruana P., Castro-Torres R.D., Ettcheto M., Leighton K.M., Olloquequi J., Steele L., Ureña J., Verdaguer E., Zárate C.B.Fuentes:scopus