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Molecular Neurobiology(7)
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scopus(37)
A metabolic perspective of late onset Alzheimer's disease
ReviewAbstract: After decades of research, the molecular neuropathology of Alzheimer's disease (AD)is still one of tPalabras claves:Alzheimer's disease, c-Jun N-terminal kinase inhibitors, Insulin, Licochalcone A, neuroinflammation, Reticulum stress, Type 2 Diabetes mellitusAutores:Antoni Camins, Auladell C., Busquets O., Cano A., Castro-Torres R.D., Ettcheto M., Folch J., García M.L., Manzine P.R., Olloquequi J., Sanchez-Lopez E., Verdaguer E., Zárate C.B.Fuentes:scopusA novel rhein-huprine hybrid ameliorates disease-modifying properties in preclinical mice model of Alzheimer’s disease exacerbated with high fat diet
ArticleAbstract: Background: Alzheimer’s disease (AD) is characterized by a polyetiological origin. Despite the globaPalabras claves:Alzheimer’s disease, BACE1, BDNF, cognitive decline, dendritic spines, high-fat diet, neuroinflammation, Rhein-huprine hybrid, Tau, TLR4Autores:Antoni Camins, Auladell C., Bulló M., Cano A., Espinosa-Jimenez T., Ettcheto M., Folch J., Muñoz-Torrero D., Olloquequi J., Parcerisas A., Pont C., Sanchez-Lopez E., Verdaguer E.Fuentes:scopusC-Jun N-Terminal Kinases in Alzheimer's Disease: A Possible Target for the Modulation of the Earliest Alterations
ReviewAbstract: Given the highly multifactorial origin of Alzheimer's disease (AD) neuropathology, disentangling andPalabras claves:Alzheimer's disease, Amyloid-β, axonal transport, hyperphosphorylated tau, JNK, synapse lossAutores:Antoni Camins, Auladell C., Busquets O., Castro-Torres R.D., Ettcheto M., Parcerisas A., Verdaguer E., Zárate C.B.Fuentes:scopusAntiapoptotic drugs: A therapautic strategy for the prevention of neurodegenerative diseases
ReviewAbstract: The purpose of this review is to discuss potential pathways involved in the pathogenesis of neurodegPalabras claves:Alzheimer's disease, apoptosis, Cyclin-dependent kinases, Glutamate receptors, Neuronal cell death, Neuroprotective drugs. apoptosis, Parkinson's DiseaseAutores:Antoni Camins, Auladell C., Canudas A.M., Folch J., Junyent F., Pallás M., Pelegrí Gabalda C., Sureda F.X., Verdaguer E., Vilaplana J., Zárate C.B.Fuentes:scopusAntiapoptotic effects of roscovitine on camptothecin-induced DNA damage in neuroblastoma cells
ArticleAbstract: In the present study dopaminergic neuroblastoma B65 cells were exposed to Camptothecin (CPT) (0.5-10Palabras claves:Ataxia telangiectasia mutated, camptothecin, cell cycle, RoscovitineAutores:Antoni Camins, Auladell C., Folch J., Junyent F., Pallás M., Pizarro J.G., Verdaguer E., Zárate C.B.Fuentes:scopusContent and traffic of taurine in hippocampal reactive astrocytes
ArticleAbstract: Taurine is one of the most abundant free amino acids in the mammalian central nervous system, wherePalabras claves:Astrogliosis, Epilepsy, Kainic acid, neuroprotection, Taurine transporterAutores:Aguado F., Antoni Camins, Auladell C., De Lemos M.L., Junyent F., Paco S., Pallás M., Romero R., Utrera J.Fuentes:scopusCorrection to: Peripheral and Central Effects of Memantine in a Mixed Preclinical Mice Model of Obesity and Familial Alzheimer’s Disease (Molecular Neurobiology, (2018), 55, 9, (7327-7339), 10.1007/s12035-018-0868-4)
OtherAbstract: The original version of this article unfortunately contained mistake. The authors found that Fig. 4.Palabras claves:Autores:Antoni Camins, Auladell C., Busquets O., Cabrera H., Carrera M.V., Carro E., Casadesús G., Ettcheto M., Folch J., García M.L., Gómez-Mínguez Y., Sanchez-Lopez E., Zárate C.B.Fuentes:scopusAging biology: A new frontier for drug discovery
ReviewAbstract: Introduction: The prevalence of age-related pathologies, such as cardiovascular disease, neurodegenePalabras claves:Autores:Antoni Camins, Auladell C., Folch J., Junyent F., Pallás M., Verdaguer E., Zárate C.B.Fuentes:scopusEarly Preclinical Changes in Hippocampal CREB-Binding Protein Expression in a Mouse Model of Familial Alzheimer’s Disease
ArticleAbstract: The molecular basis of memory loss in Alzheimer’s disease (AD), the main cause of senile dementia, iPalabras claves:Alzheimer disease, APPswe/PS1dE9, CBP, CREB, hippocampusAutores:Abad S., Antoni Camins, Auladell C., Busquets O., Carro E., Casadesús G., Ettcheto M., Folch J., Olloquequi J., Pallás M., Pedros I., Petrov D., Sanchez-Lopez E., Zárate C.B.Fuentes:scopusDual-drug loaded nanoparticles of Epigallocatechin-3-gallate (EGCG)/Ascorbic acid enhance therapeutic efficacy of EGCG in a APPswe/PS1dE9 Alzheimer's disease mice model
ArticleAbstract: Epigallocatechin-3-gallate (EGCG) is a candidate for treatment of Alzheimer's disease (AD) but its iPalabras claves:Alzheimer's disease, APP/PS1 mice, EGCG, Epigallocatechin gallate, PLGA-PEG, Polymeric nanoparticlesAutores:Antoni Camins, Auladell C., Barenys M., Barroso E., Cano A., Chang J.H., Espina M., Ettcheto M., Folch J., García M.L., Kühne B.A., Souto E.M.B., Turowski P.Fuentes:scopus