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A metabolic perspective of late onset Alzheimer's disease
ReviewAbstract: After decades of research, the molecular neuropathology of Alzheimer's disease (AD)is still one of tPalabras claves:Alzheimer's disease, c-Jun N-terminal kinase inhibitors, Insulin, Licochalcone A, neuroinflammation, Reticulum stress, Type 2 Diabetes mellitusAutores:Antoni Camins, Auladell C., Busquets O., Cano A., Castro-Torres R.D., Ettcheto M., Folch J., García M.L., Manzine P.R., Olloquequi J., Sanchez-Lopez E., Verdaguer E., Zárate C.B.Fuentes:scopusGSK3β inhibition is involved in the neuroprotective effects of cyclin-dependent kinase inhibitors in neurons
ArticleAbstract: In the present study, we evaluated the effects of roscovitine (Rosco) and flavopiridol (Flavo), bothPalabras claves:apoptosis, Cerebellar granular cells, flavopiridol, GSK3β, RoscovitineAutores:Antoni Camins, Auladell C., de la Torre A.V., Folch J., Junyent F., Pallás M., Pelegrí Gabalda C., Verdaguer E., Vilaplana J., Zárate C.B.Fuentes:scopusPI3 k/akt inhibition induces apoptosis through p38 activation in neurons
ArticleAbstract: Accumulating evidence suggests that the PI3 K/AKT pathway is a pro-survival signalling system in neuPalabras claves:Akt, BH3 only proteins, BIM, Dp5, LY294002, Neurons, p38 MAPKAutores:Antoni Camins, Auladell C., Folch J., Junyent F., Pallás M., Pelegrí Gabalda C., Vázquez De La Torre A., Verdaguer E., Vilaplana J., Zárate C.B.Fuentes:scopus