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Early amyloid accumulation in the hippocampus of SAMP8 mice
ArticleAbstract: Late-onset Alzheimer's disease (AD) is the most common form of AD appearing after 65 years of age. TPalabras claves:aging, Alzheimer's disease, Amyloid-β, Aβ40, Aβ42, AβPP, hippocampus, SAMP8, SAMR1, SenescenceAutores:Antoni Camins, Casadesús G., Del Valle J., Duran-Vilaregut J., Manich G., Pallás M., Pelegrí Gabalda C., Smith M.A., Vilaplana J.Fuentes:scopusCharacterization of amyloid-β granules in the hippocampus of SAMP8 mice
ArticleAbstract: The senescence accelerated mouse-prone 8 (SAMP8) strain of mice is an experimental model of acceleraPalabras claves:Alzheimer's disease, Amyloid-β, hippocampus, HSPG, MAP-2, SAMP8, syndecan, TauAutores:Antoni Camins, Del Valle J., Duran-Vilaregut J., Manich G., Mercader C., Pallás M., Vilaplana J.Fuentes:scopusClustered granules present in the hippocampus of aged mice result from a degenerative process affecting astrocytes and their surrounding neuropil
ArticleAbstract: Clusters of pathological granular structures appear and progressively increase in number with age inPalabras claves:aging, Astrocyte, Granules, hippocampus, Neo-epitope, Periodic acid-Schiff, SAMP8Autores:Antoni Camins, Cabezón I., Liberski P.P., Manich G., Pallás M., Pelegrí Gabalda C., Vilaplana J.Fuentes:scopusPresence of a neo-epitope and absence of amyloid beta and tau protein in degenerative hippocampal granules of aged mice
ArticleAbstract: Clustered pathological granules related to a degenerative process appear and increase progressivelyPalabras claves:aging, hippocampus, Igm, Mouse ascites Golgi, Periodic acid-Schiff, SAMP8, β-AmyloidAutores:Antoni Camins, Cabezón I., Del Valle J., Manich G., Pallás M., Pelegrí Gabalda C., Vilaplana J.Fuentes:scopus