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Journal of Allergy and Clinical Immunology(1)
Nature Genetics(1)
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scopus(3)
Familial autoinflammation with neutrophilic dermatosis reveals a regulatory mechanism of pyrin activation
ArticleAbstract: Pyrin responds to pathogen signals and loss of cellular homeostasis by forming an inflammasome complPalabras claves:Autores:Amselem S., Baker P.J., Cochet E., Copin B., Dagley L.F., De Nardo D., De Somer L., Dooley J., Goris A., Holley C.L., Jeandel P.Y., Jéru I., Josselyn E. Garcia-Perez, Lagou V., Lawless D., Liston A., Lyras D., Masters S.L., Medlej-Hashim M., Megarbane A., Moghaddas F., Nicholson S.E., Parry D.A., Pasciuto E., Ruuth-Praz J., Savic S., Schroder K., Sciot R., Van Eyck L., Van Nieuwenhove E., Webb A.I., Wouters C.H.Fuentes:scopusGenetic predisposition for beta cell fragility underlies type 1 and type 2 diabetes
ArticleAbstract: Type 1 (T1D) and type 2 (T2D) diabetes share pathophysiological characteristics, yet mechanistic linPalabras claves:Autores:Allemeersch J., Carr E.J., Chabot-Roy G., Dahlstrom J.E., Delghingaro-Augusto V., Di Marino D., Dooley J., Franckaert D., Gevaert K., Goodnow C.C., Jetten A.M., Josselyn E. Garcia-Perez, Lagou V., Lambrechts D., Laybutt D.R., Lesage S., Linterman M.A., Liston A., Lyssenko V., Nolan C.J., Oskolkov N., Overbergh L., Pasciuto E., Petrovsky N., Schlenner S.M., Schönefeldt S., Socha L., Tian L., Vandenbussche J.Fuentes:scopusCytotoxic T-lymphocyte-associated protein 4-Ig effectively controls immune activation and inflammatory disease in a novel murine model of leaky severe combined immunodeficiency
ArticleAbstract: Background: Severe combined immunodeficiency can be caused by loss-of-function mutations in genes inPalabras claves:Artemis, cytotoxic T-lymphocyte-associated protein 4, immune dysregulation, Leaky severe combined immunodeficiency, regulatory T cellAutores:Baron F., Humblet-Baron S., Josselyn E. Garcia-Perez, Liston A., Pasciuto E., Schönefeldt S.Fuentes:scopus