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Effects of Khat (Catha edulis) use on catalytic activities of major drug-metabolizing cytochrome P450 enzymes and implication of pharmacogenetic variations
ArticleAbstract: In a one-way cross-over study, we investigated the effect of Khat, a natural amphetamine-like psychoPalabras claves:Autores:Adrián LLerena, Aklillu E., Bedada W., de Andrés F., Engidawork E., Hussein J.Fuentes:scopusThe psychostimulant khat (Catha edulis) inhibits CYP2D6 enzyme activity in humans
ArticleAbstract: The use of khat (Catha edulis) while on medication may alter treatment outcome. In particular, the iPalabras claves:cathine, cathinone, CYP2D6, dextromethorphan, drug interaction, khatAutores:Adrián LLerena, Aklillu E., Beck O., Bedada W., Bertilsson L., de Andrés F., Engidawork E., Pohanka A.Fuentes:scopus