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Biochimica et Biophysica Acta - Molecular Basis of Disease(2)
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Anti-inflammatory role of Leptin in glial cells through p38 MAPK pathway inhibition
ArticleAbstract: Background In the present work, we studied the modulatory effect of Leptin (Lep) against pro-inflammPalabras claves:Caspase-3, Cytochrome-c, Glial cells, iNOS, leptin, p38 MAPKAutores:Antoni Camins, Auladell C., Busquets O., Ettcheto M., Folch J., Martí A., Martínez N., Miguel Marin, Patraca I., Pedros I., Sureda F.X., Zárate C.B.Fuentes:scopusAdipokine pathways are altered in hippocampus of an experimental mouse model of Alzheimer’s disease
ArticleAbstract: A growing body of evidence suggests that β-amyloid peptides (Aβ) are unlikely to be the only factorPalabras claves:ALZHÉIMER, APP/PS1, hippocampus, leptin, prolactinAutores:Abad S., Antoni Camins, Artiach G., Folch J., Pallás M., Pedros I., Petrov D., Ramon-Duaso C., Sureda F.X., Zárate C.B.Fuentes:scopusEvaluation of neuropathological effects of a high-fat diet in a presymptomatic Alzheimer's disease stage in APP/PS1 mice
ArticleAbstract: Alzheimer's disease (AD) is currently an incurable aging-related neurodegenerative disorder. RecentPalabras claves:Alzheimer's disease, APPswe/PS1dE9, hippocampus, insulin receptor, Mitochondria, TauAutores:Alva N., Antoni Camins, Auladell C., Carbonell T., Ettcheto M., Folch J., Pallás M., Pedros I., Petrov D., Zárate C.B.Fuentes:scopusEvaluation of the Role of JNK1 in the Hippocampus in an Experimental Model of Familial Alzheimer’s Disease
ArticleAbstract: c-Jun N-terminal kinases (JNKs), which belong to a mitogen-activated protein kinase (MAPK) family, aPalabras claves:Alzheimer’s disease, amyloid, Amyloid precursor protein, APPswe/PS1dE9, BACE1, JNK1, PGC-1α, Transgenic mouse models, β-secretase, βAAutores:Abad S., Antoni Camins, Auladell C., Ettcheto M., Folch J., Luque M., Pallás M., Pedros I., Petrov D., Verdaguer E.Fuentes:scopusEarly Preclinical Changes in Hippocampal CREB-Binding Protein Expression in a Mouse Model of Familial Alzheimer’s Disease
ArticleAbstract: The molecular basis of memory loss in Alzheimer’s disease (AD), the main cause of senile dementia, iPalabras claves:Alzheimer disease, APPswe/PS1dE9, CBP, CREB, hippocampusAutores:Abad S., Antoni Camins, Auladell C., Busquets O., Carro E., Casadesús G., Ettcheto M., Folch J., Olloquequi J., Pallás M., Pedros I., Petrov D., Sanchez-Lopez E., Zárate C.B.Fuentes:scopusEarly alterations in energy metabolism in the hippocampus of APPswe/PS1dE9 mouse model of Alzheimer's disease
ArticleAbstract: The present study had focused on the behavioral phenotype and gene expression profile of molecules rPalabras claves:Alzheimer's disease, APPswe/PS1dE9, hippocampus, insulin receptor, Mitochondria, TauAutores:Allgaier M., Antoni Camins, Auladell C., Barroso E., Casadesús G., Folch J., Pallás M., Pedros I., Petrov D., Sureda F.X., Vázquez-Carrera M., Zárate C.B.Fuentes:scopusNeuroprotective and anti-ageing role of leptin
ReviewAbstract: Leptin (Lep), an adipose-derived hormone, exerts very important functions in the body mainly on enerPalabras claves:Autores:Antoni Camins, Auladell C., Folch J., Junyent F., Pallás M., Patraca I., Pedros I., Sureda F.X., Verdaguer E., Zárate C.B.Fuentes:scopusHigh-fat diet-induced deregulation of hippocampal insulin signaling and mitochondrial homeostasis deficiences contribute to Alzheimer disease pathology in rodents
ArticleAbstract: Global obesity is a pandemic status, estimated to affect over 2 billion people, that has resulted inPalabras claves:Alzheimer disease, APPswe/PS1dE9, hippocampus, insulin receptor, Mitochondria, TauAutores:Antoni Camins, Artiach G., Barroso E., Carro E., Casadesús G., Ferrer I., Folch J., Pallás M., Pedros I., Petrov D., Sureda F.X., Vázquez-Carrera M., Zárate C.B.Fuentes:scopusHypercholesterolemia and neurodegeneration. Comparison of hippocampal phenotypes in LDLr knockout and APPswe/PS1dE9 mice
ArticleAbstract: Previous studies suggest that Alzheimer's disease (AD) neurobiology could not be explained solely byPalabras claves:Alzheimer's disease, APP/PS1, cholesterol, hippocampus, LDLR-/-, OXPHOSAutores:Alegret M., Antoni Camins, De Lemos M.L., Ettcheto M., Folch J., Laguna J.C., Pallás M., Pedros I., Petrov D.Fuentes:scopusMasitinib for the treatment of mild to moderate Alzheimer's disease
ReviewAbstract: Alzheimer's disease (AD) is a degenerative neurological disorder that is the most common cause of dePalabras claves:ALZHÉIMER, inflammation, masitinib, Neurodegeneration, TauAutores:Abad S., Antoni Camins, Auladell C., Ettcheto M., Folch J., Lazarowski A., Miguel Marin, Olloquequi J., Pedros I., Petrov D., Zárate C.B.Fuentes:scopus