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Chronic lymphocytic leukemia with proliferation centers in bone marrow is associated with younger age at initial presentation, complex karyotype, and TP53 disruption
ArticleAbstract: The presence of expanded proliferation centers (PCs) in lymph nodes involved by chronic lymphocyticPalabras claves:Bone marrow, Chronic lymphocytic leukemia/small lymphocytic lymphoma, Complex karyotype, Proliferation centers, TP53Autores:Bueso-Ramos C., Hu S., Kanagal-Shamanna R., Khoury J.D., Loghavi S., Luthra R., Medeiros L.J., Ok C.Y., Patel K.P., Routbort M.J., Salem A., Schlette E., Sofía A. Garcés, Tang G., Wang S.A.Fuentes:scopusNon-coding NOTCH1 mutations in chronic lymphocytic leukemia negatively impact prognosis
OtherAbstract:Palabras claves:Autores:Bassett R.L., Floyd K., Jain N., Jelloul F.Z., Kanagal-Shamanna R., Loghavi S., Luthra R., Medeiros L.J., Ok C.Y., Patel K.P., Routbort M.J., Sofía A. Garcés, Thompson P.A., Wang P., Wierda W.G., Yang R.K., Yin C.C., Zuo Z.Fuentes:scopusLandscape of NOTCH1 mutations and co-occurring biomarker alterations in chronic lymphocytic leukemia
ArticleAbstract: NOTCH1 is one of the most frequently mutated genes in chronic lymphocytic leukemia and has emerged aPalabras claves:Chronic lymphocytic leukemia, Coding, Non-coding, NOTCH1 mutationsAutores:Bassett R.L., Floyd K., Jain N., Jelloul F.Z., Kanagal-Shamanna R., Loghavi S., Luthra R., Medeiros L.J., Ok C.Y., Patel K.P., Routbort M.J., Sofía A. Garcés, Thompson P.A., Wierda W.G., Yang R.K., Yin C.C., Zuo Z.Fuentes:scopus