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Green Transformation of Solid-Phase Peptide Synthesis
ReviewAbstract: Peptides play key roles in medicinal chemistry, being found in therapeutics and diagnostic agents, aPalabras claves:Green Chemistry, Green solvents, Parallel synthesis, Peptide synthesis, solid-phase synthesisAutores:Alberício F., B. G. De la Torre, El-Faham A., Jad Y.E., Kumar A.Fuentes:scopusGreening the Solid-Phase Peptide Synthesis Process. 2-MeTHF for the Incorporation of the First Amino Acid and Precipitation of Peptides after Global Deprotection
ArticleAbstract: In solid-phase peptide synthesis, dichloromethane is the predominant solvent used to incorporate thePalabras claves:2-MeTHF, Dipeptide formation, incorporation, precipitation, Racemization, Solid-phase peptide synthesisAutores:Al Musaimi O., Alberício F., B. G. De la Torre, Basso A., Collins J.M., El-Faham A., Jad Y.E., Kumar A.Fuentes:scopusExploiting azido-dichloro-triazine as a linker for regioselective incorporation of peptides through their N, O, S functional groups
ArticleAbstract: In the field of bioconjugation, linker development has witnessed massive growth in recent years. 2,4Palabras claves:Bioconjuation, Linker, Orthogonal chemoselectivity, Orthogonality, Solid-phase peptide synthesisAutores:Alberício F., B. G. De la Torre, El-Faham A., Kumar A., Sharma A.Fuentes:scopusN-methylation in amino acids and peptides: Scope and limitations
ReviewAbstract: Active pharmaceutical ingbkp_redients (APIs) can be divided into two types, namely chemical and biolPalabras claves:cyclic peptides, NMAA, side-reactions, Solid-phase peptide synthesisAutores:Alberício F., B. G. De la Torre, El-Faham A., Jad Y.E., Kumar A., Monaim S.A.H.A., Sharma A.Fuentes:scopusIn situ Fmoc removal - a sustainable solid-phase peptide synthesis approach
ArticleAbstract: Solid-phase peptide synthesis (SPPS) is the strategy of choice for the synthesis of peptides for resPalabras claves:Autores:Alberício F., B. G. De la Torre, Kumar A., Sharma A.Fuentes:scopusMicrowave-Assisted Green Solid-Phase Peptide Synthesis Using γ-Valerolactone (GVL) as Solvent
ArticleAbstract: The increasing demand for synthetic peptides in various research fields raises a challenge, namely,Palabras claves:Automatic synthesis, Green solvent, peptide, Sustainable chemistryAutores:Alberício F., B. G. De la Torre, Collins J.M., Jad Y.E., Kumar A.Fuentes:scopusLiquid-Phase Peptide Synthesis (LPPS): A Third Wave for the Preparation of Peptides
ReviewAbstract: Since the last century, peptides have gained wide acceptance as drugs, with almost 100 already in thPalabras claves:Autores:Alberício F., B. G. De la Torre, Kumar A., Sharma A.Fuentes:scopusInvestigating green ethers for the precipitation of peptides after global deprotection in solid-phase peptide synthesis
ReviewAbstract: Diethyl ether and methyl tert-butyl ether are the solvents most widely used for peptide precipitatioPalabras claves:Autores:Al Musaimi O., Alberício F., B. G. De la Torre, Basso A., Collins J.M., Jad Y.E., Kumar A.Fuentes:scopusTroubleshooting When Using γ-Valerolactone (GVL) in Green Solid-Phase Peptide Synthesis
ArticleAbstract: The synthesis of peptides for both research and API production is conveniently carried out using thePalabras claves:difficult peptides, Green solvent, microwave assisted synthesis, side reactionsAutores:Alberício F., B. G. De la Torre, Collins J.M., Kumar A., Nandhini K.P., Thompson-Adewumi A.Fuentes:scopusRevisiting no<inf>2</inf> as protecting group of arginine in solid-phase peptide synthesis
ArticleAbstract: The protection of side-chain arginine in solid-phase peptide synthesis requires attention since currPalabras claves:MICROWAVE, NBP, Orthogonal protection, Protecting group, Side-reaction, Solid-phase peptide synthesis, Sonochemistry, Ultrasounds, δ-lactam formationAutores:Alberício F., Alhassan M., B. G. De la Torre, Kumar A., Lopez J.Fuentes:scopus