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1,3,5-Triazine as core for the preparation of dendrons
ArticleAbstract: A unique property of 2,4,6-trichloro-1,3,5-triazine (TCT) is its ability to undergoes a nucleophilicPalabras claves:1+2 mode, Dendron, HPLC, Nucleophiles, S-triazineAutores:Alberício F., B. G. De la Torre, El-Faham A., Kumar A., Sharma A., Sheyi R.Fuentes:scopusExploiting azido-dichloro-triazine as a linker for regioselective incorporation of peptides through their N, O, S functional groups
ArticleAbstract: In the field of bioconjugation, linker development has witnessed massive growth in recent years. 2,4Palabras claves:Bioconjuation, Linker, Orthogonal chemoselectivity, Orthogonality, Solid-phase peptide synthesisAutores:Alberício F., B. G. De la Torre, El-Faham A., Kumar A., Sharma A.Fuentes:scopusN-Butylpyrrolidinone for Solid-Phase Peptide Synthesis is Environmentally Friendlier and Synthetically Better than DMF
ArticleAbstract: Solid-phase peptide synthesis (SPPS) is the method of choice for the preparation of peptides in bothPalabras claves:aspartimide formation, Green solvent, N-butylpyrrolidinone, Racemization, Solid-phase peptide synthesisAutores:Alberício F., Alhassan M., B. G. De la Torre, Kumar A., Lopez J.Fuentes:scopusRevisiting no<inf>2</inf> as protecting group of arginine in solid-phase peptide synthesis
ArticleAbstract: The protection of side-chain arginine in solid-phase peptide synthesis requires attention since currPalabras claves:MICROWAVE, NBP, Orthogonal protection, Protecting group, Side-reaction, Solid-phase peptide synthesis, Sonochemistry, Ultrasounds, δ-lactam formationAutores:Alberício F., Alhassan M., B. G. De la Torre, Kumar A., Lopez J.Fuentes:scopusSuccessful development of a method for the incorporation of Fmoc-Arg(Pbf)-OH in solid-phase peptide synthesis using: N -butylpyrrolidinone (NBP) as solvent
ArticleAbstract: NBP has proved an excellent alternative solvent to the hazardous DMF for SPPS. Here we studied the iPalabras claves:Autores:Alberício F., Alhassan M., B. G. De la Torre, Bucher C., Kumar A., Lopez J.Fuentes:scopus