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Hepatic gene expression changes in an experimental model of accelerated senescence: The SAM-P8 mouse
ArticleAbstract: The senescence-accelerated mouse (SAM) is an experimental model of aging, established through phenotPalabras claves:inflammation, Liver, SAM mice, Xenobiotic metabolismAutores:Alegret M., Antoni Camins, Laguna J.C., Pallás M., Roglans N., Sánchez R.M., Vázquez-Carrera M., Vilà L.Fuentes:scopusHypertriglyceridemia and hepatic steatosis in senescence-accelerated mouse associate to changes in lipid-related gene expression
ArticleAbstract: Aged rodents show increasing plasma and tissue triglycerides, and reductions in liver peroxisome proPalabras claves:Autores:Alegret M., Antoni Camins, Laguna J.C., Pallás M., Roglans N., Sánchez R.M., Vázquez-Carrera M., Vilà L.Fuentes:scopusPGC-1β down-regulation is associated with reduced ERRα activity and MCAD expression in skeletal muscle of senescence-accelerated mice
ArticleAbstract: Mitochondrial dysfunction is involved in the development of aging. Here, we examined the effect of aPalabras claves:Autores:Alegret M., Antoni Camins, Coll T., Jové M., Laguna J.C., Merlos M., Pallás M., Rodríguez-Calvo R., Sánchez R.M., Vázquez-Carrera M.Fuentes:scopusPeroxisome proliferator-activated receptor α down-regulation is associated with enhanced ceramide levels in age-associated cardiac hypertrophy
ArticleAbstract: We used an experimental murine model of accelerated aging, the senescence-accelerated mouse (SAM), tPalabras claves:Autores:Alegret M., Antoni Camins, Barroso E., Coll T., Laguna J.C., Merlos M., Pallás M., Palomer X., Rodríguez-Calvo R., Sánchez R.M., Serrano L., Vázquez-Carrera M.Fuentes:scopus