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Mutant versions of von Hippel-Lindau (VHL) can protect HIF1α from SART1-mediated degradation in clear-cell renal cell carcinoma
ArticleAbstract: Inactivation of the von Hippel-Lindau (VHL) tumor suppressor drives the development of clear-cell rePalabras claves:Autores:Acosta-Iborra B., Aragonés J., Balsa E., Elorza A., Fuertes-Yebra E., Manuel Ortiz de Landázuri, Ordóñez-NavadijoFuentes:scopusInduction of the mitochondrial NDUFA4L2 protein by HIF-1α decreases oxygen consumption by inhibiting complex i activity
ArticleAbstract: The fine regulation of mitochondrial function has proved to be an essential metabolic adaptation toPalabras claves:Autores:Acosta-Iborra B., Aragonés J., Balsa E., Cadenas S., Corral-Escariz M., Elorza A., Enríquez J.A., Fuertes-Yebra E., López-Bernardo E., Manuel Ortiz de Landázuri, Martínez-Ruiz A., Ordóñez A., Perales-Clemente E., Soro I., Tello D.Fuentes:scopusMacrophage oxygen sensing modulates antigen presentation and phagocytic functions involving IFN-γ production through the HIF-1α transcription factor
ArticleAbstract: Low oxygen tension areas are found in inflamed or diseased tissues where hypoxic cells induce survivPalabras claves:Autores:Acosta-Iborra B., Aragonés J., Calzada M.J., Elorza A., Manuel Ortiz de Landázuri, Martín-Cofreces N.B., Martin-Puig S., Miro M., Olazabal I.M., Sánchez‐Madrid F.Fuentes:scopus