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Blood-pressure and cholesterol lowering in persons without cardiovascular disease
ArticleAbstract: BACKGROUND Elevated blood pressure and elevated low-density lipoprotein (LDL) cholesterol increase tPalabras claves:Autores:Accini J.L., Avezum A.J., Bosch J.J., Chazova I.E., Dagenais G.R., Dans A.M., DIaz R., Held C., Jansky P., Jung H., Keltai K., Keltai M., Khunti K., Leiter L.A., Lewis B.S., Liu L., Lonn E.M., McKelvie R., Pais P., Parkhomenko A.N., PATRICIO LOPEZ -JARAMILLO, Peters R.J.G., Piegas L.S., Pogue J., Reid C.M., Sliwa K., Toff W.D., Varigos J.D., Xavier D., Yusoff K., Yusuf S., Zhu J.Fuentes:googlescopusBlood-pressure lowering in intermediate-risk persons without cardiovascular disease
ArticleAbstract: BACKGROUND Antihypertensive therapy reduces the risk of cardiovascular events among high-risk personPalabras claves:Autores:Avezum A.J., Bosch J.J., Chazova I.E., Dagenais G.R., Dans A.M., DIaz R., Held C., Jansky P., Jung H., Keltai K., Keltai M., Khunti K., Leiter L.A., Lewis B.S., Liu L., Lonn E.M., McKelvie R., Molina D.I., Pais P., Parkhomenko A.N., PATRICIO LOPEZ -JARAMILLO, Peters R.J.G., Piegas L.S., Pogue J., Reid C.M., Sliwa K., Toff W.D., Varigos J.D., Wilkinson J., Xavier D., Yusoff K., Yusuf S., Zhu J.Fuentes:googlescopusNovel Approaches in Primary Cardiovascular Disease Prevention: The HOPE-3 Trial Rationale, Design, and Participants' Baseline Characteristics
ArticleAbstract: Background: Cholesterol and blood pressure (BP) can be effectively and safely lowered with statin drPalabras claves:Autores:Avezum A.J., Bosch J.J., Chazova I.E., Dagenais G.R., Dans A.M., DIaz R., Fodor G.J., Held C., Jansky P., Keltai K., Keltai M., Kim J.H., Kunti K., Leiter L.A., Lewis B.S., Liu L., Lonn E.M., Pais P., Parkhomenko A.N., PATRICIO LOPEZ -JARAMILLO, Peters R.J.G., Piegas L.S., Pogue J., Reid C.M., Sliwa K., Toff W.D., Varigos J.D., Xavier D., Yusoff K., Yusuf S., Zhu J.Fuentes:googlescopusLowering cholesterol, blood pressure, or both to prevent cardiovascular events: Results of 8.7 years of follow-up of Heart Outcomes Evaluation Prevention (HOPE)-3 study participants
ArticleAbstract: Aims: Rosuvastatin (10 mg per day) compared with placebo reduced major adverse cardiovascular (CV) ePalabras claves:Cardiovascular disease, Primary Prevention, statinsAutores:Avezum A.J., Bosch J.J., Dagenais G.R., Dans A.M., DIaz R., Held C., Jansky P., Joseph P.G., Jung H., Keltai K., Keltai M., Khunti K., Leiter L.A., Lewis B.S., Liu L., Lonn E.M., Pais P., Parkhomenko A.N., PATRICIO LOPEZ -JARAMILLO, Peters R.J.G., Piegas L.S., Reid C.M., Sliwa K., Toff W.D., Varigos J.D., Xavier D., Yusoff K., Yusuf S., Zhu J.Fuentes:googlescopusRationale and design of interstroke: A global case-control study of risk factors for stroke
ArticleAbstract: Stroke is a major global health problem. It is the third leading cause of death and the leading causPalabras claves:International case-control study, RISK FACTORS, strokeAutores:Avezum A.J., Chin S.L., Czlonkowska A., Damasceno A., Dans T., Devilliers L., DIaz R., Diener H.C., Hankey G.J., Kapral M., Lanas F., Langhorne P., Liu L., Mondo C.K., O’Donnell M., PATRICIO LOPEZ -JARAMILLO, Pias P., Rangarajan S., Ryglewicz D., Sacco R.L., Skowronska M., Teal P., Truelsen T., Varigos J.D., Xavier D., Yusuf S., Zhang H.Fuentes:googlescopusRationale, Design and Baseline Characteristics of Participants in the Cardiovascular Outcomes for People Using Anticoagulation Strategies (COMPASS) Trial
ArticleAbstract: Background Long-term aspirin prevents vascular events but is only modestly effective. Rivaroxaban alPalabras claves:Autores:Aboyans V., Alings M., Anand S.S., Avezum A.J., Bhatt D.L., Bosch J.J., Branch K.R.H., Bruns N.C., Chen E., Commerford P.J., Connolly S.J., Dagenais G.R., Dans A.M., DIaz R., Eikelboom J.W., Ertl G., Felix Camilo, Fox K.A.A., Guzik T.J., Ha J.W., Hart R.G., Hori M., Kakkar A.K., Keltai K., Keltai M., Kim J.H., Lamy A., Lanas F., Lanius V., Leong D.P., Lewis B.S., Liang Y., Liu L., Lonn E.M., Maggioni A.P., Metsarinne K.P., Misselwitz F., Moayyedi P., O’Donnell M., Parkhomenko A.N., PATRICIO LOPEZ -JARAMILLO, Piegas L.S., Pogosova N., Probstfield J.L., Rydén L.E., Sharma M., Steg P.G., Störk S., Tonkin A.M., Torp-Pedersen C., Varigos J.D., Verhamme P.B., Vinereanu D., Widimsky P., Yuan F., Yusoff K., Yusuf S., Zhu J.Fuentes:googlescopusRationale, design, and baseline participant characteristics in the MRI and cognitive substudy of the cardiovascular outcomes for people using anticoagulation strategies trial
ArticleAbstract: Background: Covert vascular disease of the brain manifests as infarcts, white matter hyperintensitiePalabras claves:Anticoagulant, Clinical trial, COGNITION, magnetic resonance imaging, prevention, silent infarctAutores:Avezum A.J., Berkowitz S.D., Bhatt D.L., Bosch J.J., Branch K.R.H., Casanova A., Connolly S.J., Cook-Bruns N., Dagenais G.R., DIaz R., Eikelboom J.W., Ertl G., Fox K.A.A., Ha J.W., Hart R.G., Keltai K., Keltai M., Kim J.H., Liang Y., Liu L., Lonn E.M., Maggioni A.P., O’Donnell M., PATRICIO LOPEZ -JARAMILLO, Piegas L.S., Pogosova N., Probstfield J.L., Rydén L.E., Sharma M., Smith E.E., Störk S., Tonkin A.M., Varigos J.D., Vinereanu D., Wong G., Yuan F., Yusuf S., Zhu J.Fuentes:googlescopusRivaroxaban for Prevention of Covert Brain Infarcts and Cognitive Decline: The COMPASS MRI Substudy
ArticleAbstract: Background and Purpose: Covert brain infarcts are associated with cognitive decline. It is not knownPalabras claves:aspirin, COGNITION, infarction, rivaroxaban, white matterAutores:Avezum A.J., Berkowitz S.D., Bhatt D.L., Bosch J.J., Branch K.R.H., Casanova A., Connolly S.J., Dagenais G.R., DIaz R., Dyal L., Eikelboom J.W., Ertl G., Fox K.A.A., Hart R.G., Keltai K., Keltai M., Kim J.H., Liang Y., Liu L., Lonn E.M., Maggioni A.P., O’Donnell M., PATRICIO LOPEZ -JARAMILLO, Piegas L.S., Pogosova N., Probstfield J.L., Reeh K.W., Rydén L.E., Sharma M., Smith E.E., Störk S., Tonkin A.M., Varigos J.D., Vinereanu D., Yusuf S., Zhu J.Fuentes:googlescopusRivaroxaban with or without aspirin in patients with stable coronary artery disease: an international, randomised, double-blind, placebo-controlled trial
ArticleAbstract: Background: Coronary artery disease is a major cause of morbidity and mortality worldwide, and is aPalabras claves:Autores:ABIB E., ABRANTES J.A., AHUAD GUERRERO R.A., ALBISU DI GENNERO J.P., ALVAREZ M., Anand S.S., Avezum A.J., Barbieri M., BARTOLACCI I.P., Berkowitz S.D., Bhatt D.L., BORDONAVA A.P., Bosch J.J., Branch K.R.H., CACCAVO A., CARDONA M., CARTASEGNA L.U.I.S., Chacón C., Connolly S.J., Cook-Bruns N., COSTABEL J.P., CUADRADO J., Cuneo C.A., Dagenais G.R., Dans A.M., DEBONNAIRE P., DRAN R.D., DUJARDIN K.A.R.L., Dyal L., ECTOR B.A.V.O., Eikelboom J.W., ELEGEERT I.V.A.N., Felix Camilo, FERRE PACORA F.A., Fox K.A.A., GARCIA DURAN R.O., GARRIDO M., Gomez Vilamajo O., GONZALEZ COLASO P.D.C., GRINFELD D., Guzik T.J., GUZMAN L.U.I.S., Ha J.W., HASBANI E., HERNANDES M., HOFFER E., HOMINAL M.A., Hori M., HRABAR A., IBANEZ SAGGIA L.M., INDIO DO BRASIL C., Ingaramo A., Keltai K., Lanas F., LEROY J.E.A.N., LITVAK BRUNO M.R., Liu L., Lonn E.M., LUCIARDI H.L., LUQUEZ H.U.G.O., MACIN S.M., MACKINNON I.J., MAFFEI L.E., Maggioni A.P., Maia L.N., MAJUL C.R., MANENTI E., Metsarinne K.P., Montaña O., NANI S., Novaretto L., O’Donnell M., Parkhomenko A.N., PELAGAGGE M.J., Precoma D.B., RECH R., Reis G., ROSSI DOS SANTOS F., ROSSI P., SALA J., SARAIVA J.O.S.E., SARJANOVICH R.J., SCHIAVI L.B., SCHROE H., SCHYGIEL P.O., Torp-Pedersen C., VAN DE BORNE P., VAN DEN HEUVEL P.A.U.L., Varigos J.D., VENSENTINI N., Verhamme P.B., VICO M., VITA N.A., VOGEL D., VRANCKX P., Widimsky P., Yusoff K., Yusuf S., ZAIDMAN C., ZIMMERMANN S.L.Fuentes:googlescopusPractice patterns and outcomes after stroke across countries at different economic levels (INTERSTROKE): an international observational study
ArticleAbstract: Background: Stroke disproportionately affects people in low-income and middle-income countries. AlthPalabras claves:Autores:Agapay S., Avezum A.J., Bladin C.F., CACCAVO A., Carcamo D., Carvalho A., Carvalho J.J., Casanova A., Cedrolla C.M., Chin S.L., Correa Vila Nova D., Czlonkowska A., Damasceno A., Daniel Tettamanti, Dans A.M., Dehghan M., Dejesus J., Della Vedova B., Desmery P.M., Devanath A., DIaz R., Diener H.C., Dowlatshahi D., Duran R.G., ElSayed A., Ferraz de Almeida A.C., Friedrich M., Garrote M., Gates P., Gebara O., Gladstone D., Gupta R., Hall K., Hankey G.J., Herkes G., Hernandez M.E., Huerta M.F., Hussain F.A., Iqbal R., Islam S., Iversen H.K., Kabali C., Keys J., Kraemer T., Lanas F.T., Langhorne P., Liu L., MacLeod M.J., Magazi D., Málaga G., Mathur N., McQueen M.J., Minelli C., Minuzzo L., Molinos J., Mondo C.K., Mota D.M., Nilanont Y., Nofal P.G., O'Donnell M., Ogah O.S., Ogunniyi A., Oguz A., Oliveira D.C., Oliveira L., Ouriques Martins S.C., Oveisgharan S., O’Donnell M., PATRICIO LOPEZ -JARAMILLO, Peñaherrera E., Pereira M.P., Pogosova N., Prabhakaran D., Rangarajan S., Rao-Melacini P., Reis H., Ritt L.E., Rodriguez M.A., Rosengren A., Rumboldt Z., Ryglewicz D., SCHYGIEL P.O., Shuaib A., Silver F., Silvia Cáceres, Sobral Sousa A.C., Sposato L., Teal P., Teixeira M., Turner M., Valdez P., Varigos J.D., Wang X., Wasay M., Weimar C., Xavier D., Yan Duarte, Yusoff K., Yusuf S., Yusufali A.M., Zhang H., Zhang X.M., Zurru M.C.Fuentes:googlescopus