Current considerations in the differential diagnosis of amelanotic melanoma and possible pitfalls

Abstract:

found using BW 2501183, which should react with CEA or NCA 95 only. Thus in our experiment nearly half of the positive reactions for CEA in melanomas could be explained by a cross-reaction with NCA. Generally speaking, two points should always be borne in mind when evaluating immunohistochemical results in the GI-tract and its tumours. First, the epithelial cells all arise from common stem cells at the bottom of the crypts. These cells have the capacity for developing into absorptive cells, mucin producing cells, Paneth cells, endocrine cells, micro fold cells and others. Occasionally such cells are present in unusual locations. Well-known examples are pyloric type glands and Paneth cells in the regenerative colorectal mucosa after severe inflammation and Paneth cells and endocrine cells in adenomas and carcinomas. Less common examples are primary MM or squamous carcinoma in intestinal mucosa …

Año de publicación:

1993

Keywords:

Fuente:

google