Cyclohexyl sulphones for treatment of cancer

Abstract:

Nickoloff, BJ et al. Oncogen, vol. 22, pp. 6598-6608 (2004),“Notch signaling as a therapeutic target in cancer: a new approach to the development of cell fate modifying agents'. McKenzie, GJ et al., Expert Opinion on Therapeutic Targets, vol. 9 (2), pp. 395-410 (2005),“Notch: a unique therapeutic target for immunomodulation'. Qin, JZetal. Molecular Cancer Therapeutics, vol. 3 (8), pp. 895-902 (2004),“p53-independent NOXA induction overcomes apoptotic resistance of malignant melanomas'. van Es, JH et al., Nature, vol. 435, pp. 959-963 (2005),“Notch/y-Secretase inhibition turns proliferative cells in intestinal crypts and adenomas into goblet cells'. Callahan, R et al., Journal of Mammary Gland Biology and Neoplasia, vol. 9 (2), pp. 145-163 (2004),“Notch signaling in mam mary development and oncogenesis'. Collins, BJ et al., Seminars in Cancer Biology, vol. 14, pp. 357-364 (2004),“Notch in lung development and …

Año de publicación:

2013

Keywords:

Fuente:

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