About the mechanisms of renoprotective effect of angiotensin inhibitors on lupus nephritis

Abstract:

To the Editor: During the past years C2 monitoring of cyclosporine microemulsion (CsA) has been focused on as a new, improved, and possibly more “correct” monitoring regimen in transplant recipients [1–3]. I read with great interest the publication by Perico et al [4] in Kidney International. They concluded that among serial daily CsA measurements post-transplant, a CsA trough blood concentration of 300 to 440 ng/mL (and not C2) taken as early as day 2 has by far the highest capacity to pbkp_redict rejection episodes. These results diverge from most recent publications. I register, however, that it is not stated in the text or in the tables or figures how many patients that were actually included in their final analysis. When reading the article, one gets the impression that 224 patients (334 patients minus 110 patients with delayed graft function) were included. From Table 3, which only includes data from 16 patients, one can …

Año de publicación:

2004

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Fuente:

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