Depuración de procalcitonina en pacientes con sepsis neonatal del Hospital Abel Gilbert entre 2014-2015

Abstract:

Neonatal sepsis is an important cause of death in critically ill patients, especially in developing countries. In Latin America, the incidence of neonatal sepsis is between 3.5 and 8.9 percent. In Ecuador, according to the INEC, in 2010, sepsis in the neonatal period occupied the sixth cause of infant morbidity and the fifth cause of mortality, not counting its associated problems such as necrotizing enterocolitis or congenital pneumonia. And at the level of the Abel Gilbert Pontón Hospital in the NICU area, I was the second cause of morbidity and mortality. Currently we do not have a rapid technique, which compares with the cultures, can negatively influence the mortality of patients with neonatal sepsis. This study aims to determine the clearance of procalcitonin as a prognostic biomarker of Sepsis. Objectives: To determine the frequency of performance as pbkp_redictive value of procalcitonin clearance in patients with neonatal sepsis. Establish the association between positive cultures and clearance of procalcitonin. Association between days of hospitalization and clearance of procalcitonin Methodology: This is a study with a quantitative approach that requires a descriptive epidemiological design of clinical and clinical cases of a transverse type applied to 52 clinical records of patients with definitive diagnosis of neonatal sepsis in the NICU area. Abel Gilbert Pontón Hospital with retrospective follow-up between 2014-2015. In this study we used the serial values of PCT onset and on the 3rd day to perform the clearing formula. RESULTS: The studied population of 53 patients (57.6%) (n = 30) was male, 42.4% (n = 23) female. The median age was 4 days, median days of hospitalization 12 days, but the patients with the longest stay in neonatal intensive care were 38% of the total population. Positive cultures or 44.2%. Klebsiella pneumoniae and E.coli being the most xiv frequent with 20.8%. The PCT levels at the beginning medina 1.2ng / ml, and PCT 3er diameter 1.3ng / ml and the PCTc cutoff was greater than -22%. Conclusion: It has been observed that the use of the PCT series as an optimal support in the admission and allowed to perform the same treatment and can conclude that it is a good pbkp_redictor of the main hospital stay in neonatal intensive care and is reflected Elevated PCT levels were higher in patients with mortality

Año de publicación:

2017

Keywords:

• Epidemiologia Descriptiva
• ECUADOR
• CANTÓN GUAYAQUIL
• Hospital de Especialidades Guayaquil Dr. Abel Gilbert Pontón
• Polipéptido alfa relacionado con calcitonina
• Sepsis neonatal

Fuente:

rraae