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Detection and sequencing of Zika virus in normocephalic newborns with congenital Zika infection

Abstract:

Fourteen asymptomatic normocephalic newborns with confirmed congenital Zika infection were investigated. All newborns presented Zika virus (ZIKV) positivity on reverse transcriptase polymerase chain reaction. Following ZIKV-specific NS5 gene fragment sequencing in one child, phylogenetic analysis revealed that this isolate belonged to the Asian genotype, and clustered closely with other sequences previously isolated in north-east and northern regions of Brazil.

Año de publicación:

2022

Keywords:

  • Phylogenetic analysis
  • Zika Virus
  • Congenital infection
  • Viral sequencing

Fuente:

scopusscopus

Tipo de documento:

Article

Estado:

Acceso abierto

Áreas de conocimiento:

  • Infección

Áreas temáticas:

  • Enfermedades
  • Medicina forense; incidencia de enfermedades
  • Ginecología, obstetricia, pediatría, geriatría

Contribuidores:

De Almeida B.L.De Almeida B.L.
Oliveira J.V.V.Oliveira J.V.V.
Leão E.K.E.d.A.Leão E.K.E.d.A.
Lucena R.Lucena R.
de Oliveira J.M.G.C.de Oliveira J.M.G.C.
Calcagno J.I.Calcagno J.I.
Carneiro M.W.Carneiro M.W.
Isadora Cristina de SiqueiraIsadora Cristina de Siqueira
Pellegrini R.Pellegrini R.
Alcantara L.C.J.Alcantara L.C.J.
Giovanetti M.Giovanetti M.
Salles C.Salles C.
Faiçal A.V.B.Faiçal A.V.B.
Carvalho T.X.Carvalho T.X.
Figueiredo E.M.Figueiredo E.M.
Acosta A.X.Acosta A.X.
Agra I.A.Agra I.A.