Diagnostic Electron Microscopy and Immunohistochemistry Part I: Neoplastic Diseases

Abstract:

There has been much progress in the development of ancillary diagnostic techniques in Anatomic Pathology in the past 50 years. Histochemical and ultrastructural methods preceded the development of flow-cytometry and immunohistochemistry, revolutionizing the way diagnostic problems were approached by pathologists. The existing paradigm years ago, in which the most experienced pathologist rendered a final diagnosis in controversial cases, which was unconditionally accepted by peers, became fallible. The new diagnostic techniques became available to test probable diagnoses suggested by the most experienced. In a way, the ancillary techniques served at times as an “equalizer” between experienced and less mature pathologists. The most recent additions to the armamentarium of diagnostic techniques that pathologists have at their disposal to address diagnostic challenges have been cytogenetics …

Año de publicación:

2002

Keywords:

Fuente:

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