Diastereoselective Synthesis of (±)-Ambrox by Titanium(III)-Catalyzed Radical Tandem Cyclization

Abstract:

A synthesis of (±)-ambrox, a compound with delicious ambergris-type scent, is presented. The key step is a highly diastereoselective titanocene(III)-catalyzed radical tandem cyclization of a farnesol derivative.

Año de publicación:

2016

Keywords:

• Natural products
• Titanocene
• ambrox
• radical chemistry
• diastereoselective synthesis

Fuente:

scopus