Addison's Disease


Abstract:

The term 'Addison's disease' is synonymous with primary adrenal insufficiency. In Addison's days, the most common etiology was infectious adrenal destruction, usually due to tuberculosis. Among the many etiologies, autoimmune adrenalitis is the most common form in developed countries, but infectious, infiltrative, genetic, and traumatic forms also occur. The diagnosis is based on low serum cortisol and aldosterone in the face of high-plasma adrenocorticotropin and renin, either basal or after cosyntropin stimulation. Treatment consists of glucocorticoid and mineralocorticoid replacement for life, with increased doses during severe physical stress or illness.

Año de publicación:

2014

Keywords:

  • Adrenal gland
  • cortisol
  • Dehydroepiandrosterone
  • Hypotension
  • aldosterone
  • Addison's disease
  • Adrenal insufficiency
  • Adrenoleukodystropy
  • mineralocorticoid
  • Waterhouse-Friderichsen syndrome
  • Glucocorticoid

Fuente:

scopusscopus

Tipo de documento:

Book Part

Estado:

Acceso restringido

Áreas de conocimiento:

    Áreas temáticas:

    • Enfermedades

    Contribuidores: