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Aging control with resveratrol

Abstract:

The prevalence of age-related pathologies such as neurodegenerative disease and diabetes type II has increased with rise in average age of people. Finding antiaging molecules is necessary to prevent or delay the alterations taking place in age which are manifested as age-associated illnesses. Currently, dietary restriction (DR) is one of the most effective antiaging interventions. Thus, the biochemical pathways involved in DR lifespan increase are under intensive investigation. Sirtuin 1 and mTOR (mammalian target of rapamycin) are two well characterized antiaging pathways. Resveratrol constitutes a natural compound which mimics the effects of DR with potential application on age-associated diseases and thus as antiaging therapy. © 2011 Elsevier Ltd. All rights reserved.