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Effect of gender on the left ventricular response to supine exercise in healthy subjects

Abstract:

This study characterized gender-related differences in the left ventricular response to supine exercise. The study group included untrained healthy volunteers (30 women and 25 men) who underwent equilibrium exercise radionuclide angiography. Men and women had an equivalent rest ejection fraction (EF)(0.67+/-0.08 vs 0.67+/-0.06), whereas at exercise a significantly greater increase was seen in men (12%+/-6% vs 5%+/-3%)(F< 0.001). Men had a greater end-diastolic (ED) volume at rest and at peak exercise. During exercise, a mild increase in end diastolic volume index was seen in both sexes (12%+/-9% in men and 10%+/-8% in women). The end-systolic (ES) volume sharply decreased in the two groups (31%+/-15% in men compared with 16%+/-9% in women)(P< 0.001). These results indicated gender-related differences in the left ventricular response to supine exercise and confirm previous findings in …