Eficacia del tratamiento farmacológico inicial del sangrado digestivo alto en cirróticos según los hallazgos endoscópicos obtenidos

Abstract:

This study was focused on cirrhotic patients who had upper gastrointestinal bleeding, and due to its pathophysiological and morbidity-mortality inclusions, this type of bleeding is divided into two groups: variceal bleeding secondary to portal hypertension, and nonvariceal bleeding. the one presented by peptic ulcer. Methodology: analytical, correlational, cross-sectional, retrospective cohort study where 97 patients with digestive cirrhosis who presented upper digestive bleeding were included at Teodoro Maldonado Carbo Hospital during the period from January 1, 2019 to December 31, 2020. Objective: To determine the efficacy of the initial pharmacological treatment of upper digestive bleeding in cirrhotic patients according to the endoscopic findings obtained at the Teodoro Maldonado Carbo Hospital during the period from January 1, 2019 to December 31, 2020. Objective: To determine the efficacy of the initial pharmacological treatment of upper digestive bleeding in cirrhotic patients according to the endoscopic findings obtained at the Teodoro Maldonado Carbo Hospital during the period from January 1, 2019 to December 31, 2020. Results: it was shown that the association of inhibitors of the proton pump (PPI), to the already known treatment in upper gastrointestinal bleeding in cirrhotic patients that are derivatives of somatostatin plus prophylactic antibiotic therapy was justified since in this study of 97 patients the non-variceal etiology was representative in 52 patients with 53.61%, having a sensitivity: 79.59% and specificity: 94.23% in the endoscopic findings obtained from no active digestive bleeding. Conclusion: to highlight the importance of the protocol use of the PPI as initial pharmacological treatment in the emergency area, since its use in this study revealed a very representative sensitivity and specificity for not finding active digestive bleeding during the diagnostic endoscopy, thus we were able to provide a treatment I integrate these patients and reduce their risk of mortality. Keywords: liver cirrhosis, upper gastrointestinal bleeding, proton pump inhibitors

Año de publicación:

2022

Keywords:

• HEMORRAGIA GASTROINTESTINAL
• Epidemiologia Analitica
• ESTUDIOS RETROSPECTIVOS
• CIRROSIS HEPÁTICA
• CANTÓN GUAYAQUIL
• ECUADOR
• Hospital De Especialidades Dr. Teodoro Maldonado Carbo

Fuente:

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