Alkylation of some pyrimidine and purine derivatives using microwave-assisted methods

Abstract:

N-Alkylation of adenine (1), guanine (2) and 6-amino-2-thiouracil (3) with different halides has been carried out using microwave-assisted methods in the presence of small amounts of DMF to improve energy transfer and in the case of 3 by coupling with phase transfer catalysis. The results obtained show high yields and selectivities.

Año de publicación:

2001

Keywords:

Fuente:

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