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Epidemiological clinical behavior of Behçet's disease

Abstract:

Introduction: Behç et's disease is defined as a vasculitis affecting all types of vessels, presenting with local and systemic clinical manifestations that may involve concern any organ or organ system. Objective: To describe the clinical and epidemiological behaviour of Behç et's disease in Cuba. Methods: An observational, longitudinal, retrospective, and descriptive study was conducted on a group of 8 patients with Behç et's disease, who were evaluated and followed-up by the National Rheumatology Centre of the "10 October" Clinical Surgical Hospital, Havana, Cuba. Results: The mean age of the 8 patients (6 women and 2 men) found was 47 ± 17 years old. The most common clinical manifestations were oral (100%) and genital (100%) ulcers, and bone, muscle and joint system involvement, followed by psychological disorders (62.5%). An increased C-reactive protein (100%) was the most common laboratory finding. Colchicine (100%), combined with steroids and methotrexate (87.5%) is the most commonly treatment used. Conclusions: There was a predominance of females and patients over 40 years, with a higher incidence of general symptoms, oral and genital ulcers, arthralgia, arthritis, and psychological disorders. Combined therapy with steroids, methotrexate and colchicine was the most commonly found.