1-Year outcomes following bioprosthetic valve fracture to facilitate valve-in-valve transcatheter aortic valve replacement

Abstract:

Background: Bioprosthetic valve fracture (BVF) improves the hemodynamic results of valve-in-valve transcatheter aortic valve replacement (VIV TAVR) by facilitating optimal expansion of the transcatheter heart valve (THV). Long-term outcomes following BVF are unknown. Methods: Consecutive cases of VIV TAVR and BVF (n = 139) performed at 11 sites were analyzed retrospectively. Hemodynamic measurements and aortic valve area (AVA) were assessed during the procedure and by echocardiography at 30-day and 1-year follow-up. Results: VIV TAVR and BVF resulted in significant improvements in mean valve gradient (42.3 ± 17.1 vs. 9.4 ± 5.8 mmHg, p < 0.001) and AVA (0.8 ± 0.4 vs. 1.8 ± 0.7 cm2, p < 0.001) compared with baseline. Mortality was 2.3% at 30 days and 8.7% at 1-year. In adjusted models, mean valve gradient was higher (+5.1 [3.7, 6.5] mmHg, p < 0.001) and AVA was lower (−0.3 [−0.4, −0.2] cm …

Año de publicación:

2021

Keywords:

Fuente:

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