Regresar

Analysis of the most efficient autosomal strs and genetic data for the locus se33 in ecuadorian population

Abstract:

Twenty three autosomal STR markers were analyzed to define which are the most informative in forensic genetic cases in Ecuadorian population. In this study, we report genetic data from 1434 and 1800 unrelated individuals for SE33 and other 22 STRs, respectively. The parameters analyzed were: polymorphism information content (PIC), heterozygosity, power of discrimination and power of exclusion. SE33 was the best marker for forensic identification purposes because it showed the highest polymorphism information content (PIC) of 0.9334; heterozygosity of 0.9191; power of discrimination of 0.9969 and power of exclusion of 0.8345. Hence, we recommend its use in routine and complex paternity cases. After SE33, the subsequent most informative STR markers for Ecuadorian population were PENTA E, FGA, D1S1656 and D19S433, and the less informative markers were VWA, D22S1045, D2S441, TPOX and D3S1358.