Evaluation of the prevention program for vertical transmission of HIV virus in a Public Hospital. Babahoyo–Ecuador

Abstract:

Introduction: vertical transmission is the most common way of transmitting the HIV virus during the perinatal period. Without any intervention, an estimated 20% of infants will become infected before birth. Objective: to evaluate vertical transmission prevention treatment by measuring the effectiveness, adherence and safety of antiretroviral treatment in a Public Hospital of Babahoyo-Ecuador. Method: a descriptive study was performed on all HIV-positive pregnant women treated at the Martin Icaza Hospital in Babahoyo during the period 2014 to 2015. The variables measured were program effectiveness, as demonstrated by the number of HIV-positive newborns; adherence to treatment and safety of antiretroviral treatment demonstrated by reporting adverse effects, changes in hematological/hepatic profiles, CD4 lymphocyte count, and viral load. Results: the main results of the evaluation of 40 cases of pregnant women with HIV with the HAART treatment of: tenofovir+ emtricitabine+ efavirenz. The efficacy in vertical transmission was 100%, with 0 cases of infected newborns. Adherence to treatment was 95%. The regimen used proved to be safe for patients despite a slight significant increase in their liver profiles. In 93% of pregnant women there were no adverse effects and those that were reported had minor effects: headache and nausea. Conclusions: it was evidenced the protection of HAART avoiding the vertical transmission of pregnant mothers infected by HIV, promoted by their adherence to the treatment and the low occurrence of adverse effects.

Año de publicación:

2017

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Fuente:

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