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FRI0302 Sjögren’s syndrome and associated organ-specific autoimmune diseases: clinical, immunological and histological profile. argentine study group of sjögren´ s syndrome …

Abstract:

Background Sjögren’s Syndrome is the most common connective tissue disease that appears in association with other autoimmune diseases. Objectives To determine if significant differences exist in the clinical, immunological and histological profile between patients with pSS with an associated organ-specific autoimmune disease (AAD) and patients without it. Methods It was analyzed the data included in the GESSAR’s database. Eight organ-specific autoimmune diseases were selected: Autoimmune Thyroiditis (AT), Primary Biliary Cirrhosis (PBC), Autoimmune Hepatitis (AH), Celiac Disease (CD), Primary Sclerosing Cholangitis (PSC), Ulcerative Colitis (UC), Crohn’s Disease (CR) and Vitiligo (VT). Two groups of patients with pSS were obtained: one with organ-specific AAD and another one without it. The following variables were analyzed: 1-Associated organ-specific autoimmune disease, 2-clinical profile …