Female adnexal tumor of probable wolffian origin. Case report

Abstract:

The female adnexal tumor of probable Wolffian origin is an unusual and little-known neoplasm, originally described as a tumor originating from the remnants of the mesonephric duct in areas where these remnants are abundant. The histopathological presentation can cause important diagnosis confusion. The preoperative diagnosis is very difficult due to the rarity of the disease and the limited literature available. Due to its malignant potential, after initial surgical treatment patients should be evaluated adequately for possible recurrence and development of metastasis. We present a case of a female adnexal tumor of probable wolffian origin in a 50-year-old patient with pain and abdominal distension of 3 weeks of evolution. The patient had a history of total hysterectomy with left oophorosalpingectomy. Transvaginal ultrasound and computed tomography confirmed the presence of a 14 x 10 x 8 cm right ovarian tumor with a normal CA-125 value. The patient underwent exploratory laparotomy. In the histological evaluation, the cellular atypia was minimal and the mitotic activity very low. The cells were strongly positive for pancytokeratin, cytokeratin 7, vimentin and calretinin with positivity focused for inhibin and CD10. These were negative for estrogen and progesterone receptors, chromogranin, carcinoembryo-genic antigen, epithelial membrane antigen, CD99, and CD117.

Año de publicación:

2019

Keywords:

• Wolff tumor
• Female adnexal tumor
• Mesonephric tumor
• Ovary
• Immunohistochemistry

Fuente:

scopus