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Folate fortification of rice by metabolic engineering

Abstract:

Rice, the world's major staple crop, is a poor source of essential micronutrients, including folates (vitamin B9). We report folate biofortification of rice seeds achieved by overexpressing two Arabidopsis thaliana genes of the pterin and para-aminobenzoate branches of the folate biosynthetic pathway from a single locus. We obtained a maximal enhancement as high as 100 times above wild type, with 100 g of polished raw grains containing up to four times the adult daily folate requirement. © 2007 Nature Publishing Group.

Año de publicación:

2007

Keywords:

    Fuente:

    scopusscopus

    Tipo de documento:

    Article

    Estado:

    Acceso restringido

    Áreas de conocimiento:

    • Biotecnología

    Áreas temáticas:

    • Bioquímica
    • Ingeniería química

    Contribuidores:

    Blancquaert D.Blancquaert D.
    Lambert W.Lambert W.
    Oscar NavarreteOscar Navarrete
    De Brouwer V.De Brouwer V.
    Zhang G.F.Zhang G.F.
    Van Der Straeten D.Van Der Straeten D.
    Storozhenko S.Storozhenko S.
    Volckaert M.Volckaert M.