Antimicrobial Activity of Skin Secretions of Hyloscirtus Frogs

Abstract:

The inappropriate use of antibiotics has generated serious problems of bacterial resistance. A great diversity of antibiotic resistance genes has been found in studies of bacterial genomes from humans and environment; this antibiotics are prescribed freely, producing serious impacts on human, animal and environmental health, with the consequent alteration of the normal microbiota. Generate new drugs for the inhibition of the big variety of microorganisms is a difficult objective and the appearance of new resistant strains is rapid; therefore, the exploration of new compounds has focused on Antimicrobial Peptides (AMPs) that come from the skin of amphibians. That is why the present work focuses on the analysis of the antimicrobial effect of the total skin secretions of two species of frogs of the Hylidae family, which until now have not been studied: Hyloscirtus pantosticus and Hyloscirtus lindae.

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