Antinociceptive and anti-inflammatory effects of Croton malambo bark aqueous extract

Abstract:

Croton malambo (K.) bark aqueous extract, popularly known in Venezuela as "palomatias" or "torco" was tested for acute toxicity and for its anti-inflammatory and antinociceptive effects using tail flick and writhing syndrome tests models, respectively. Croton malambo aqueous extract (6.15 mg/kg i.p.) administered intraperitoneally had a significant antinociceptive and anti-inflammatory effects compared to acetylsalicylic acid (200 mg/kg p.o.) and sodium diclofenac (5.64 mg/kg p.o.). Studies to determine correlation between chemical composition and pharmacological activity are underway. © 2003 Elsevier Ireland Ltd. All rights reserved.

Año de publicación:

2003

Keywords:

• Aqueous extract
• Croton malambo
• Analgesic
• anti-inflammatory activity

Fuente:

scopus