Fractal Changes in the Long-Range Correlation and Loss of Signal Complexity in Infant’s Heart Rate Variability with Clinical Sepsis

Abstract:

Sepsis, a critical bacterial infection of the bloodstream, is a frequent cause of illness and death in premature infants in the neonatal intensive care units. A prospective analysis was conducted of the inter–beat-intervals time series (IBI) derived from 1 hour 30 minutes electrocardiogram (ECG) recordings for 14 episodes of clinical sepsis in 90 infants 12-18 hour old in the maternity ward of the Consorcio-Hospital General Universitario de Valencia. The aim was to test the hypothesis that normal beat-to-beat fluctuations in heart rate show fractal long-range correlations and that pathological condition reduce the adaptive capacity of the individual degrading the information carried by their signals and modifying the fractal scaling characteristics. Fractal properties of these series were evaluated by applying the method of Detrended Fluctuation Analysis (DFA) for the quantification of the correlation property in the …

Año de publicación:

2014

Keywords:

Fuente:

google