Regresar

GLYCATED HEMOGLOBIN AS A LIMIT MARKER FOR EARLY DIAGNOSIS OF DIABETES MELLITUS IN OVERWEIGHT PATIENTS (METABOLIC SYNDROME)

Abstract:

The incidence of diabetes mellitus (DM) and overweight have increased in recent years, both globally and in Ecuador. DM and overweight are closely related and are triggers for cardiovascular, kidney, eye, and nerve (DM) complications and can also contribute to the development of metabolic syndrome. The main purpose of this study was to analyze whether glycated hemoglobin values could be used as a limit marker for earlier diagnosis of type 2 DM in overweight patients. This was a nonexperimental, analytical, retrospective, longitudinal study of 100 overweight patients diagnosed with type 2 DM. The study was carried out in 2014 at Teodoro Maldonado Carbo Hospital, Guayaquil, Ecuador. We collected and analyzed data including variables such as sex, A1C, DM, obesity, family history of type 2 DM, and levels of cholesterol, triglycerides, high-density lipoprotein, and low-density lipoprotein. As a result, a biplot analysis was performed that showed no straightforward relationship between body mass index and A1C or fasting glucose. However, a significant relationship was found between patients with hypertriglyceridemia, overweight-obesity, and A1C. Finally, an A1C level of 5.55% to 6% was determined to be a pbkp_redictor value, but there were not enough criteria to diagnose a pbkp_rediabetic state in patients linked to overweight and hypertriglyceridemia. However, further studies must be performed to define diagnostic values. We need to determine the percentage of body fat, postprandial glucose level, and clinical symptomatology that can be used as clinical parameters.