Gas exchange assessment at rest and during exercise in patients with Eisenmenger syndrome

Abstract:

PURPOSE: To assess gas exchange and distribution of ventilation in Eisenmenger syndrome patients at rest and while performing submaximal exercise at an altitude of 2240 mts above sea level. METHODS: 93 patients with Eisenmenger syndrome due to ASD 49p, VSD 27p, PDA 20p; 74 females, 19 males. Age 36±14 (20-73) yo, height 1.53±0.1 m, weight 59±17 Kg. PAP 98±27 mmHg, PaO2 50±8 mmHg, VA shunt QsQt% 14.9±5, Hb gr/dl 17.7±4.2. Gas exchange (GE) was assessed in 70 p at room air (ra), FiO2 1 (100%) and at the end of exercise (e). Independent student t test; p< 0.05 was considered as significative when compared to ra values also regression analysis with SPSS 10 was applied to data. RESULTS: Spirometry; FEV1 mls. 1877±646; FEV1% 70±18, FEVI/FVC% 78±14, FEF% 56±30. GE is presented in table 1. A trend to decrease in PaO2 and pH was observed at the end of exercise although not …

Año de publicación:

2005

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Fuente:

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