Genomic Bayesian pbkp_rediction model for count data with genotype × environment interaction


Abstract:

Genomic tools allow the study of the whole genome, and facilitate the study of genotype-environment combinations and their relationship with phenotype. However, most genomic pbkp_rediction models developed so far are appropriate for Gaussian phenotypes. For this reason, appropriate genomic pbkp_rediction models are needed for count data, since the conventional regression models used on count data with a large sample size (nT) and a small number of parameters (p) cannot be used for genomic-enabled pbkp_rediction where the number of parameters (p) is larger than the sample size (nT). Here, we propose a Bayesian mixed-negative binomial (BMNB) genomic regression model for counts that takes into account genotype by environment (G×E) interaction. We also provide all the full conditional distributions to implement a Gibbs sampler. We evaluated the proposed model using a simulated data set, and a real wheat data set from the International Maize and Wheat Improvement Center (CIMMYT) and collaborators. Results indicate that our BMNB model provides a viable option for analyzing count data.

Año de publicación:

2016

Keywords:

  • Shared data resource
  • Bayesian model
  • GenPred
  • Gibbs sampler
  • Genomic selection
  • Count data
  • Genome enabled pbkp_rediction

Fuente:

scopusscopus

Tipo de documento:

Article

Estado:

Acceso abierto

Áreas de conocimiento:

    Áreas temáticas:

    • Microorganismos, hongos y algas
    • Fisiología humana