4-N-aryl(benzyl)amino-4-heteroaryl-1-butenes as building blocks in heterocyclic synthesis. 2. Synthesis of new tetrahydro-2-benzazepine derivatives and related compounds containing a pyridine ring

Abstract:

Chemical transformations of the aminobutenes (1,2) were studied. Their allyl cationic intramolecular cyclisation led to the preparation of new tetrahydro-2-benzazepines containing a pyridine ring (3,4). The acylation and oxidation reactions of these aminobutenes gave several amides (5,6,8) and nitrone (7a), which was converted into the 6-phenyl-2-(3-pyridyl)-7-oxa-1-azabicyclo[2.2.1]heptane (9a).

Año de publicación:

2002

Keywords:

Fuente:

scopus