Haematological reference intervals in Highland Andean Ecuadorian Population, using the Sysmex XE-21000 blood counter

Abstract:

Introduction: Hemogram is the most frequently ordered test for the evaluation of the health status of an individual. Its reference values are important in people that live in altitude, because of the decrease in the partial pressure of oxygen that affects the hemoglobin concentration, the hematocrit and other hematimetric parameters. In Quito, the last study of reference intervals was performed in 1985, using manual methods. Material and methods: A descriptive epidemiological survey research study was performed. A sample of 2,613 hemograms was selected from adults of both sexes, and ages ranging from 18 to 45 years of age, submitted to Net-L@ b SA (Quito), all of them performed for preventive health studies using the blood counter Sysmex XE-2100®. Results: The average age of the subjects studied was 28.76±7.6 years, and 53.6% of the subjects were males. Significative differences were found between the reference intervals calculated in this study and those reported in other publications about populations from different altitudes. The differences occurred in all the parameters evaluated, even if compared with populations located at a similar altitude than Quito. Conclusions: These results underline the necessity for all laboratories to calculate the reference intervals from their own populations, or to justify the utilization of reference intervals calculated in other populations.

Año de publicación:

2008

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