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Hemoglobin variants and hematologic and serologic parameters of the population of El Limón (Aragua State, Venezuela)

Abstract:

Nine hundred and fifty seven individuals from El Limon (Aragua State, Venezuela) were studied, in order to get information on their hematologic, immunologic and biochemical characteristics. The majority of surnames were of Spanish origin although there were also from other European nationalities. No surname from Venezuelan Indians was found. The pathologic hemoglobin variants (Hb S, Hb C and Hb D-Punjab) have a frequency of 4.3%. Eight albumin variants were detected. The hematologic values suggest a high frequency of iron deficiency. Positivity for hepatitis virus B was found in 0.9% of the population. The carriers and patients for hemoglobin variants per generation was calculated for the whole municipality (5062 and 26, respectively). The African component of the population was estimated in around 18%.