Hexafluoroacetone as protecting and activating reagent. Glycosylated malic, citramalic, and thiomalic acid derivatives, new glycosylated building blocks for drug design

Abstract:

Glycosylated α-hydroxy and α-mercapto acids have been synthesized starting from malic/citramalic/thiomalic acid and Ac 4-β-D-Glc-NH2/Bzl4-β-D-Glc-NH 2 using hexafluoroacetone as protecting and activating reagent. © Springer-Verlag 2004.

Año de publicación:

2004

Keywords:

• 3-Hydroxysuccinimido sugars
• α-Mercapto acids
• N-Glycosylated depsipeptides
• Dielectrophiles
• Glycosylamines
• Maleimido sugars
• α-Hydroxy acids
• α-Hydroxyacylamino acids
• α-Mercaptoacylamino acids

Fuente:

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