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Human Interleukin 2: Production by Both T<inf>G</inf> Cells and Other T Cells

Abstract:

We have investigated the production of interleukin 2 (IL‐2) by human T cells after their stimulation by phytohaemagglutinin (PHA). T cells isolated by rosetting with sheep erythrocytes produced high levels of IL‐2. Further separation of rosette‐forming cells, according to the expression of Fc receptors for IgG, showed that TG and non‐TG cells are equally able to produce IL‐2. The release of IL‐2 by TG cells did not require DNA synthesis or functional Fey receptors, since positively selected TG cells produced IL‐2, even though they lacked lymphoproliferative responses to PHA and antibody‐dependent cell‐mediated cytotoxicity. Copyright © 1981, Wiley Blackwell. All rights reserved

Año de publicación:

1981

Keywords:

    Fuente:

    scopusscopus

    Tipo de documento:

    Article

    Estado:

    Acceso restringido

    Áreas de conocimiento:

    • Inmunología
    • Inmunología

    Áreas temáticas:

    • Fisiología y materias afines
    • Enfermedades
    • Farmacología y terapéutica

    Contribuidores:

    ALVAREZ J.M.ALVAREZ J.M.
    SILVA A.G.SILVA A.G.
    Manuel Ortiz de LandázuriManuel Ortiz de Landázuri
    Bonnard G.D.Bonnard G.D.